Category Archives: Children or Youth (less than 18 years old)
Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
Background: Preventing active tuberculosis (TB) from developing in people with latent tuberculosis infection (LTBI) is important for global TB control. Isoniazid (INH) for six to nine months has 60% to...
Screening for HIV: Systematic review to update the 2005 U.S. Preventive Services Task Force recommendation
BACKGROUND: A 2005 U.S. Preventive Services Task Force (USPSTF) review found good evidence that HIV screening is accurate and that antiretroviral therapy (ART) for immunologically advanced disease is associated with...
Immunomodulatory effects of intravenous immunoglobulins (IVIGs) in HIV-1 disease: A systematic review
Intravenous immunoglobulins (IVIGs) are generally used as replacement therapy for humoral immunodeficiencies. In consideration of their immune-modulating properties, they are also employed as “immune-modulating/ anti-inflammatory” treatment in different clinical conditions....
Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: A systematic review of randomized trial including more than 2800 women
Background: Observational studies have suggested that low serum vitamin levels are associated with increased mother-to-child transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of...
Social support and HIV-related risk behaviors: A systematic review of the global literature
Existing empirical evidence has well documented the role of social support in both physical and psychological well-being among various populations. In the context of HIV prevention, the rapid increase of...
Improved access to early infant diagnosis is a critical part of a child-centric prevention of mother-to-child transmission agenda
BACKGROUND: Prevention-of-mother-to-child-transmission (PMTCT) programs have made it possible to achieve dramatic reductions in the rate of vertical HIV transmission. However, high attrition, particularly after delivery, has limited the impact of...
Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: A systematic review and meta-analysis
OBJECTIVE: To determine whether cotrimoxazole reduces mortality in adults receiving antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection in low- and middle-income countries through a systematic review and meta-analysis....
Systematic review on the etiology and antibiotic treatment of pneumonia in human immunodeficiency virus-infected children
BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality in human immunodeficiency virus (HIV)-infected children. OBJECTIVES AND METHODS: A systematic review of studies that were published between...
Flu and pneumococcal immunisations in HIV-infected children: Methodological quality of current recommendations
OBJECTIVE: To assess the quality of guidelines, consensus statements and systematic reviews on flu and pneumococcal immunisations in HIV-infected children. METHOD: The authors screened PubMed and Embase databases until the...
Interventions to improve adherence to antiretroviral therapy in children with HIV infection
BACKGROUND: Achieving and maintaining high levels of medication adherence are required to achieve the full benefits of antiretroviral therapy (ART), yet suboptimal adherence among children is common in both developed...
