Category Archives: Children or Youth (less than 18 years old)
Nutritional interventions for reducing morbidity and mortality in people with HIV
Background: Adequate nutrition is important for optimal immune and metabolic function. Dietary support may, therefore, improve clinical outcomes in HIV-infected individuals by reducing the incidence of HIV-associated complications and attenuating...
Effectiveness of sport-based HIV prevention interventions: A systematic review of the evidence.
Interest in sport as a tool for behavioral HIV prevention has grown substantially in the past decade. With dozens of organisations now using sport-based HIV prevention (SBHP) approaches and upcoming...
Iron supplementation for reducing morbidity and mortality in children with HIV
BACKGROUND: The most prevalent haematologic disturbance associated with HIV in children (apart from CD4 lymphocytopenia) is anaemia. Anaemia associated with HIV arises from multiple mechanisms, including the direct inhibitory effect...
Prevalence and risk of violence and the physical, mental, and sexual health problems associated with human trafficking: Systematic review
There is very limited evidence on the health consequences of human trafficking. This systematic review reports on studies investigating the prevalence and risk of violence while trafficked and the prevalence...
Interventions to prevent HIV/AIDS among adolescents in less developed countries: Are they effective?
The objective of this study was to summarize and critically assess the effects of interventions to prevent HIV/AIDS among adolescents in less developed countries. Reports of studies that evaluated interventions...
Persistent difficulties in switching to second-line ART in sub-saharan Africa — A systematic review and meta-analysis
OBJECTIVES: Switching to second-line antiretroviral therapy (ART) largely depends on careful clinical assessment and access to biological measurements. We performed a systematic review and meta-analysis to estimate the incidence of...
Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children
BACKGROUND: Oral candidiasis (OC) associated with human immunodeficiency virus (HIV) infection occurs commonly and recurs frequently, often presenting as an initial manifestation of the disease. Left untreated, these lesions contribute...
Resistance at virological failure using boosted protease inhibitors versus nonnucleoside reverse transcriptase inhibitors as first-line antiretroviral therapy–implications for sustained efficacy of ART in resource-limited settings
BACKGROUND: Increases in the prevalence of resistance to nonnucleoside reverse transcriptase inhibitors (NNRTIs) have been observed among previously untreated individuals in all areas of sub-Saharan Africa. We aimed to examine...