Category Archives: Children or Youth (less than 18 years old)
Assessing stigma in low- and middle-income countries: A systematic review of scales used with children and adolescents
INTRODUCTION: Stigmatization contributes to health inequalities, impacting the wellbeing of children and adolescents negatively. Addressing stigmatization requires adequate measurement. Our systematic review synthesizes the content of scales used with children...
The proportion of loss to follow-up from antiretroviral therapy (ART) and its association with age among adolescents living with HIV in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) remains a global health threat, especially in developing countries. The successful scale-up of antiretroviral therapy (ART) programs to address this threat is hindered by a...
Implementation science for the prevention and treatment of HIV among adolescents and young adults in sub-Saharan Africa: A scoping review
Despite many evidence-based adolescent and young adult (AYA) HIV interventions, few are implemented at scale in sub-Saharan Africa (SSA). A growing implementation science literature provides important context for scaling up...
Barriers and facilitators to HIV prevention interventions for reducing risky sexual behavior among youth worldwide: A systematic review
BACKGROUND: Interventions aimed at reducing risky sexual behavior are considered an important strategy for averting Human Immunodeficiency Virus (HIV) infection among youth (15-24Aÿyears) who continue to be at risk of...
Health-related needs reported by adolescents living with HIV and receiving antiretroviral therapy in sub-Saharan Africa: A systematic literature review
INTRODUCTION: Adolescents living with HIV (ALHIV) on antiretroviral therapy (ART) have specific health needs that can be challenging to deliver. Sub-Saharan Africa (SSA) is home to 84% of the global...
Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis
Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...
Pediatrics HIV-positive status disclosure and its predictors in Ethiopia: A systematic review and meta-analysis
INTRODUCTION: HIV-positive status disclosure for children is challenging for family members, guardians, and healthcare professionals. Disclosure is very challenging, particularly for children, yet no systematic synthesis of evidence accurately measures...
Storyboarding HIV infected young people’s adherence to antiretroviral therapy in lower- to upper middle-income countries: A new-materialist qualitative evidence synthesis
Young people living with perinatal infections of Human Immunodeficiency Virus (YLPHIV) face a chronic disease, with treatment including adherence to lifelong antiretroviral treatment (ART). The aim of this QES was...
Malaria prevalence in HIV-positive children, pregnant women, and adults: A systematic review and meta-analysis
Background: Malaria in human immunodeficiency virus (HIV)-positive patients is an ever-increasing global burden for human health. The present meta-analysis summarizes published literature on the prevalence of malaria infection in HIV-positive children,...
Rethinking mental health wellness among adolescents living with HIV in the African context: An integrative review of mental wellness components
OBJECTIVE: Adolescents living with HIV (ALHIV) are considered to be at heightened risk for developing mental health problems in comparison to their peers due to the burden of living with...
A systematic review of digital interventions to improve ART adherence among youth living with HIV in sub-Saharan Africa
An estimated 3.4 million youth aged 15–24 years live with human immunodeficiency virus (HIV), a majority of whom reside in sub-Saharan Africa (SSA). Youth living with HIV (YLHIV) generally maintain...
