Category Archives: People who use drugs

The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia

2016

Despite global reductions in HIV incidence and mortality, the 15 UNAIDS-designated countries of Eastern Europe and Central Asia (EECA) that gained independence from the Soviet Union in 1991 constitute the...

Impact of opioid substitution therapy on antiretroviral therapy outcomes: A systematic review and meta-analysis

2016

BACKGROUND: Human immunodeficiency virus (HIV)-infected people who inject drugs (PWID) frequently encounter barriers accessing and remaining on antiretroviral therapy (ART). Some studies have suggested that opioid substitution therapy (OST) could...

Association of opioid agonist therapy with the initiation of antiretroviral therapy — A systematic review

2016

OBJECTIVES: People who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART). Evidence is available about...

Prevalence and burden of HCV co-infection in people living with HIV: A global systematic review and meta-analysis

2016

BACKGROUND: At global level, there are 37 million people infected with HIV and 115 million people with antibodies to hepatitis C virus (HCV). Little is known about the extent of...

A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs

2016

To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...

The influence of neurocognitive impairment on HIV risk behaviors and intervention outcomes among high-risk substance users: A systematic review

2016

Neurocognitive impairment (NCI) among high-risk substance users poses a substantial barrier to reducing risk behaviors in this population. Previous work suggests that NCI is intertwined in a close, reciprocal relationship...

Comparisons of adherence to antiretroviral therapy in a high-risk population in China: A systematic review and meta-analysis

2016

BACKGROUND: Reports on antiretroviral therapy (ART) adherence are scare in China; we performed this meta-analysis to estimate ART adherence rates in different populations at high risk for HIV transmission in...

Implementing HIV testing in substance use treatment programs: A systematic review

2015

People who use drugs are at increased risk for HIV acquisition, poor engagement in health care, and late screening for HIV with advanced HIV at diagnosis and increased HIV-related morbidity,...

Attitudes and acceptability on HIV self-testing among key populations: A literature review

2015

HIV self-testing (HIVST) is a potential strategy to overcome disparities in access to and uptake of HIV testing, particularly among key populations (KP). A literature review was conducted on the...

Providing comprehensive health services for young key populations: Needs, barriers and gaps

2015

INTRODUCTION: Adolescence is a time of physical, emotional and social transitions that have implications for health. In addition to being at high risk for HIV, young key populations (YKP) may...

HIV and human herpesvirus 8 co-infection across the globe: Systematic review and meta-analysis

2016

HIV-infection is an important risk factor for developing Kaposi sarcoma (KS), but it is unclear whether HIV-positive persons are also at increased risk of co-infection with human herpesvirus 8 (HHV-8),...

Global epidemiology of HIV among women and girls who use or inject drugs: Current knowledge and limitations of existing data

2015

BACKGROUND: Women and girls who use and inject drugs are a critical population at risk of HIV. In this article, we review data on the epidemiology of drug use and...

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