Category Archives: People who use drugs
Association of opioid agonist therapy with the initiation of antiretroviral therapy — A systematic review
OBJECTIVES: People who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART). Evidence is available about...
Amphetamine-type stimulants and HIV infection among men who have sex with men: Implications on HIV research and prevention from a systematic review and meta-analysis
INTRODUCTION: HIV infections and the use of amphetamine-type stimulants (ATS) among men who have sex with men (MSM) have been increasing internationally, but the role of ATS use as a...
Influence of different drugs on HIV risk in people who inject: Systematic review and meta-analysis
AIMS: To systematically assess risk of HIV acquisition by type of drug injected across different settings. METHODS: A systematic review and meta-analysis were conducted. Databases were searched for studies of...
Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis
OBJECTIVES: Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual populations in both high-income and...
HIV prevention for adults with criminal justice involvement: A systematic review of HIV risk-reduction interventions in incarceration and community settings
We summarized and appraised evidence regarding HIV prevention interventions for adults with criminal justice involvement. We included randomized and quasi-randomized controlled trials that evaluated an HIV prevention intervention, enrolled participants...
Substance abuse treatment in persons with HIV/AIDS: Challenges in managing triple diagnosis
Clinical management of HIV must account for the “triple diagnosis” of HIV, psychiatric diagnosis, and substance use disorders and requires integrated treatment services that focus beyond just mitigation of substance...
Effects of HIV antiretroviral therapy on sexual and injecting risk-taking behavior: A systematic review and meta-analysis.
BACKGROUND: Increased global access and use of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by changing individual risk-taking behavior. This review...
Drug-drug interactions with antiviral agents in people who inject drugs (PWID) requiring substitution therapy
OBJECTIVE: To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy,...