Category Archives: People who use drugs

Impact of opioid substitution therapy on antiretroviral therapy outcomes: A systematic review and meta-analysis

2016

BACKGROUND: Human immunodeficiency virus (HIV)-infected people who inject drugs (PWID) frequently encounter barriers accessing and remaining on antiretroviral therapy (ART). Some studies have suggested that opioid substitution therapy (OST) could...

Effectiveness and safety of oral HIV preexposure prophylaxis for all populations

2016

OBJECTIVE: Preexposure prophylaxis (PrEP) offers a promising new approach to HIV prevention. This systematic review and meta-analysis evaluated the evidence for use of oral PrEP containing tenofovir disoproxil fumarate as...

Association of opioid agonist therapy with the initiation of antiretroviral therapy — A systematic review

2016

OBJECTIVES: People who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART). Evidence is available about...

Prevalence and burden of HCV co-infection in people living with HIV: A global systematic review and meta-analysis

2016

BACKGROUND: At global level, there are 37 million people infected with HIV and 115 million people with antibodies to hepatitis C virus (HCV). Little is known about the extent of...

A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs

2016

To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...

The influence of neurocognitive impairment on HIV risk behaviors and intervention outcomes among high-risk substance users: A systematic review

2016

Neurocognitive impairment (NCI) among high-risk substance users poses a substantial barrier to reducing risk behaviors in this population. Previous work suggests that NCI is intertwined in a close, reciprocal relationship...

Comparisons of adherence to antiretroviral therapy in a high-risk population in China: A systematic review and meta-analysis

2016

BACKGROUND: Reports on antiretroviral therapy (ART) adherence are scare in China; we performed this meta-analysis to estimate ART adherence rates in different populations at high risk for HIV transmission in...

Implementing HIV testing in substance use treatment programs: A systematic review

2015

People who use drugs are at increased risk for HIV acquisition, poor engagement in health care, and late screening for HIV with advanced HIV at diagnosis and increased HIV-related morbidity,...

Attitudes and acceptability on HIV self-testing among key populations: A literature review

2015

HIV self-testing (HIVST) is a potential strategy to overcome disparities in access to and uptake of HIV testing, particularly among key populations (KP). A literature review was conducted on the...

Providing comprehensive health services for young key populations: Needs, barriers and gaps

2015

INTRODUCTION: Adolescence is a time of physical, emotional and social transitions that have implications for health. In addition to being at high risk for HIV, young key populations (YKP) may...

Global epidemiology of HIV among women and girls who use or inject drugs: Current knowledge and limitations of existing data

2015

BACKGROUND: Women and girls who use and inject drugs are a critical population at risk of HIV. In this article, we review data on the epidemiology of drug use and...

Recreational drug use among individuals living with HIV in Europe: Review of the prevalence, comparison with the general population and HIV guidelines recommendations

2015

BACKGROUND: Adherence problems, interactions and higher rate of risk activities have been observed in HIV individuals using recreational drugs. Our aim was to describe recreational drug use in both HIV...

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