Category Archives: People who use drugs

Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa

2015

HIV testing and counselling is the first crucial step for linkage to HIV treatment and prevention. However, despite high HIV burden in sub-Saharan Africa, testing coverage is low, particularly among...

Examining non-AIDS mortality among people who inject drugs

2014

OBJECTIVE: To systematically review and analyse data from cohorts of people who inject drugs (PWID) to improve existing estimates of non-AIDS mortality used to calculate mortality among PWID in the...

Adherence to antiretroviral medications among persons who inject drugs in transitional, low and middle income countries: An international systematic review

2015

Adherence to antiretroviral (ART) medication is vital to reducing morbidity and mortality among HIV positive persons. People who inject drugs (PWID) are at high risk for HIV infection in transitional/low/middle...

Revitalizing the HIV response in Pakistan: A systematic review and policy implications

2014

BACKGROUND: We sought to describe the epidemiology of HIV in Pakistan and prioritize interventions to improve the effectiveness and efficiency of the response to HIV. METHODS: We conducted a systematic...

Amphetamine-type stimulants and HIV infection among men who have sex with men: Implications on HIV research and prevention from a systematic review and meta-analysis

2015

INTRODUCTION: HIV infections and the use of amphetamine-type stimulants (ATS) among men who have sex with men (MSM) have been increasing internationally, but the role of ATS use as a...

Influence of different drugs on HIV risk in people who inject: Systematic review and meta-analysis

2015

AIMS: To systematically assess risk of HIV acquisition by type of drug injected across different settings. METHODS: A systematic review and meta-analysis were conducted. Databases were searched for studies of...

Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis

2014

OBJECTIVES: Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual populations in both high-income and...

HIV prevention for adults with criminal justice involvement: A systematic review of HIV risk-reduction interventions in incarceration and community settings

2014

We summarized and appraised evidence regarding HIV prevention interventions for adults with criminal justice involvement. We included randomized and quasi-randomized controlled trials that evaluated an HIV prevention intervention, enrolled participants...

Substance abuse treatment in persons with HIV/AIDS: Challenges in managing triple diagnosis

2014

Clinical management of HIV must account for the “triple diagnosis” of HIV, psychiatric diagnosis, and substance use disorders and requires integrated treatment services that focus beyond just mitigation of substance...

HIV, HCV, and health-related harms among women who inject drugs: Implications for prevention and treatment

2015

BACKGROUND: Although an estimated 3.5 million women inject drugs globally, women are outnumbered 4 to one by men who inject drugs and are often ignored or overlooked in the development...

Effects of HIV antiretroviral therapy on sexual and injecting risk-taking behavior: A systematic review and meta-analysis.

2014

BACKGROUND: Increased global access and use of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by changing individual risk-taking behavior. This review...

Drug-drug interactions with antiviral agents in people who inject drugs (PWID) requiring substitution therapy

2015

OBJECTIVE: To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy,...

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