Category Archives: People who use drugs

Interventions to prevent HIV and Hepatitis C in people who inject drugs: A review of reviews to assess evidence of effectiveness

2014

BACKGROUND: Injecting drug use is a major risk factor for the acquisition and transmission of HIV and Hepatitis C virus (HCV). Prevention of these infections among people who inject drugs...

HIV and hepatitis B and C incidence rates in US correctional populations and high risk groups: A systematic review and meta-analysis

2010

BACKGROUND: High Human Immunodeficiency Virus (HIV) prevalence and high risk behaviors have been well documented within United States (US) correctional systems. However, uncertainty remains regarding the extent to which placing...

Using respondent-driven sampling methodology for HIV biological and behavioral surveillance in international settings: A systematic review

2008

To determine operational and analytical characteristics of respondent-driven sampling (RDS) in international settings and to explore factors that may affect recruitment of most-at-risk populations using RDS, we reviewed HIV biological...

Non-occupational postexposure prophylaxis for HIV: A systematic review

2009

OBJECTIVES: To review the evidence on the clinical effectiveness and cost-effectiveness of non-occupational postexposure prophylaxis (PEP) for HIV. DATA SOURCES: Eleven electronic databases were searched from inception to December 2007....

Non-injection drug use and HIV disease progression in the era of combination antiretroviral therapy

2011

Little is known about the effects of non-injection drug use (NIDU) on HIV antiretroviral treatment outcomes. We conducted a systematic literature search and identified nine publications from prospective cohort studies...

Effectiveness of HIV prevention interventions in developing countries

2000

Objective: To review the effectiveness of projects and programs in developing countries that aim to reduce sexual transmission of HIV infection or transmission related to injection drug use. Design: We...

HIV-1 molecular epidemiology evidence and transmission patterns in the Middle East and North Africa

2011

The distribution of HIV-1 subtypes in a population tracks the spread and evolution of the epidemic. This study is a systematic review of all available evidence on HIV-1 molecular epidemiology...

Effectiveness of structural-level needle/syringe programs to reduce HCV and HIV infection among people who inject drugs: A systematic review

2013

Needle-syringe programs (NSP) have been effective in reducing HIV and hepatitis C (HCV) infection among people who inject drugs (PWID). Achieving sustainable reductions in these blood-borne infections requires addressing structural...

Efficacy of interventions in improving highly active antiretroviral therapy adherence and HIV-1 RNA viral load: A meta-analytic review of randomized controlled trials

2006

Summary: Adherence to highly active antiretroviral therapy (HAART) is generally suboptimal, limiting the effectiveness of HAART. This meta-analytic review examined whether behavioral interventions addressing HAART adherence are successful in increasing...

Does opioid substitution treatment in prisons reduce injecting-related HIV risk behaviours? A systematic review

2010

OBJECTIVES: To review systematically the evidence on opioid substitution treatment (OST) in prisons in reducing injecting-related human immunodeficiency virus (HIV) risk behaviours. METHODS: Systematic review in accordance with guidelines of...

AIDS in Latin America: Assessing the current status of the epidemic and the ongoing response

2008

Background: This article provides a summary of the current status of the HIV/AIDS epidemic in Latin America, as well as an outline of the diverse responses to it. Methods: A...

Drug use as a driver of HIV risks: Re-emerging and emerging issues

2014

PURPOSE OF REVIEW: We reviewed the studies published in 2012–013 that focused on re-emerging and emerging injection and noninjection drug use trends driving HIV risk behaviors and transmission in some...

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