Category Archives: People who use drugs

Drug use as a driver of HIV risks: Re-emerging and emerging issues

2014

PURPOSE OF REVIEW: We reviewed the studies published in 2012–013 that focused on re-emerging and emerging injection and noninjection drug use trends driving HIV risk behaviors and transmission in some...

Heterosexual risk of HIV infection in China: Systematic review and meta-analysis

2011

BACKGROUND: Heterosexual sex has become the dominant transmission route in China. Recently studies reported high heterogeneity in heterosexual transmission risk in resource-limited countries. The aim of this study was to...

Epidemiology of HIV among female sex workers, their clients, men who have sex with men and people who inject drugs in West and Central Africa

2013

INTRODUCTION: The West and Central Africa (WCA) sub-region is the most populous region of sub-Saharan Africa (SSA), with an estimated population of 356 million living in 24 countries. The HIV...

Barriers of enrolment in HIV vaccine trials: A review of HIV vaccine preparedness studies

2011

Barriers to participation in an HIV vaccine trial have been examined in many HIV vaccine preparedness studies (VPS). These barriers can be understood in terms of the locus of the...

Can hepatitis C virus prevalence be used as a measure of injection-related human immunodeficiency virus risk in populations of injecting drug users? An ecological analysis

2010

BACKGROUND: Human immunodeficiency virus (HIV) outbreaks occur among injecting drug users (IDUs), but where HIV is low insight is required into the future risk of increased transmission. The relationship between...

The effectiveness and safety of syringe vending machines as a component of needle syringe programmes in community settings

2008

Syringe vending machines (SVMs) have been introduced in Europe and Australasia as part of the effort to increase the availability of sterile needles and syringes to injecting drug users (IDUs)....

A systematic review of antiretroviral adherence interventions for HIV-infected people who use drugs

2012

HIV-infected persons who use drugs (PWUDs) are particularly vulnerable for suboptimal combination antiretroviral therapy (cART) adherence. A systematic review of interventions to improve cART adherence and virologic outcomes among HIV-infected...

The HIV Modes of Transmission model: A systematic review of its findings and adherence to guidelines

2014

INTRODUCTION: The HIV Modes of Transmission (MOT) model estimates the annual fraction of new HIV infections (FNI) acquired by different risk groups. It was designed to guide country-specific HIV prevention...

HIV drug resistance assessment in the Western Pacific region. A systematic review

2011

Antiretroviral therapy is being rapidly scaled-up in Western Pacific region countries. Prevention and assessment of HIV drug resistance is an essential component of successful global antiretroviral therapy scale-up. We performed...

Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: A systematic review and meta-analysis

2014

BACKGROUND: Needle and syringe programmes (NSP) aim to reduce the risk of HIV by providing people who inject drugs (PWID) with sterile injecting equipment. A recent review of reviews (ROR)...

What data are available on the extent of illicit drug use and dependence globally? Results of four systematic reviews

2011

BACKGROUND: We systematically reviewed availability and quality of data on the prevalence of use and dependence on meth/amphetamine, cannabis, cocaine and opioids. METHODS: Multiple search strategies: (a) peer-reviewed literature searches...

Meta-analyses on behavioral interventions to reduce the risk of transmission of HIV

2009

Different behavioral interventions have found to be efficacious in reducing high-risk sexual activity. Interventions have been evaluated in both original research and meta-analytic reviews. Most of the studies have shown...

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