Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Delivery of HIV test results, post-test discussion and referral in health care settings: A review of guidance for European countries
OBJECTIVES: HIV testing and counselling (HTC) guidelines support and promote best practice among service providers. Few European countries have national HTC guidelines and most rely on guidance from regional and...
Hormonal contraceptive use and women’s risk of HIV acquisition: A meta-analysis of observational studies
BACKGROUND: The evidence from epidemiological research into whether use of hormonal contraception increases women’s risk of HIV acquisition is inconsistent. We did a robust meta-analysis of existing data to provide...
Treatment of multicentric Castleman’s disease in HIV-1 infected and uninfected patients: A systematic review
BACKGROUND: Multicentric Castleman’s disease (MCD) is frequently associated with human-herpesvirus (HHV)-8, especially in human immunodeficiency virus (HIV)-1 co-infections. The optimal treatment is unclear. This systematic review provides an overview of...
Systematic review exploring time trends in the association between educational attainment and risk of HIV infection in sub-Saharan Africa
OBJECTIVE: To assess the evidence that the association between educational attainment and risk of HIV infection is changing over time in sub-Saharan Africa. DESIGN AND METHODS: Systematic review of published...
Cytotoxic T-lymphocyte responses to canarypox vector-based HIV vaccines in HIV-seronegative individuals: A meta-analysis of published studies
PURPOSE: A successful prophylactic HIV vaccine will probably require neutralizing antibodies and vigorous CTL (CD8+ T-cytotoxic lymphocyte) responses. Canarypox vector-based HIV vaccines (ALVAC-HIV) have been gaining momentum as promising HIV...
Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection
Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...
Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis
BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...
Low levels of HIV test coverage in clinical settings in the U.K.: A systematic review of adherence to 2008 guidelines
OBJECTIVES: To quantify the extent to which guideline recommendations for routine testing for HIV are adhered to outside of genitourinary medicine (GUM), sexual health (SH) and antenatal clinics. METHODS: A...
Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review
AIM: To investigate the diagnosis, pathogenesis, natural history, and management of nodular regenerative hyperplasia (NRH) in patients with human immunodeficiency virus (HIV). METHODS: We performed a systematic review of the...
A systematic review of interventions to reduce HIV-related stigma and discrimination from 2002 to 2013: How far have we come?
Introduction: HIV-related stigma and discrimination continue to hamper efforts to prevent new infections and engage people in HIV treatment, care and support programmes. The identification of effective interventions to reduce...
Systematic review of antiretroviral-associated lipodystrophy: Lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction
BACKGROUND: Lipoatrophy and/or central fat gain are observed frequently in patients on antiretroviral therapy (ART). Both are assumed to be antiretroviral adverse drug reactions. METHODS: We conducted a systematic review...
