Category Archives: General HIV- population

Reviews on HIV- people that explore topics including risk, screening, and prevention

Systemic preexposure prophylaxis for HIV: Translating clinical data to clinical practice

2014

OBJECTIVE: To assess the real-world implications of oral tenofovir-emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. DATA SOURCES: A search of...

The influence of religion on sexual HIV risk

2014

This systematic review examines the relationship between religion and sexual HIV risk behavior. It focuses primarily on how studies have conceptualized and defined religion, methodologies, and sexual risk outcomes. We...

A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: Rethinking the significance of serological non-responsiveness and the serofast state after therapy

2015

BACKGROUND: Syphilis remains a global public health threat and can lead to severe complications. In addition to resolution of clinical manifestations, a reduction in nontreponemal antibody titers after treatment is...

Incentivizing HIV/STI testing: A systematic review of the literature.

2014

Suboptimal HIV/STI testing uptake has a profound impact on morbidity and mortality. Incentives have been effective in other areas of medicine and may improve HIV/STI testing uptake rates. This study...

Microbicide acceptability research: Current approaches and future directions

2005

With growing recognition of the potential value of microbicides for HIV/STI prevention, the importance of the acceptability of this brand-new technology has been widely acknowledged. We review the current body...

Cost-effectiveness of community-level approaches to HIV prevention: A review

2002

Effective community-level HIV prevention strategies have the potential to reach large numbers of at-risk individuals at relatively small per-capita costs, and therefore to be highly cost-effective. We review the published...

Persistent difficulties in switching to second-line ART in sub-saharan Africa — A systematic review and meta-analysis

2013

OBJECTIVES: Switching to second-line antiretroviral therapy (ART) largely depends on careful clinical assessment and access to biological measurements. We performed a systematic review and meta-analysis to estimate the incidence of...

Social network-based interventions to promote condom use: A systematic review

2011

Effective sexually transmitted infection (STIs)/HIV prevention programs are urgently needed, but translating evidence-based methods of STI/HIV prevention into sustainable programs has been difficult. Social influences are critical for establishing condom...

Evaluation of brief screening tools for neurocognitive impairment in HIV/AIDS: A systematic review of the literature

2013

OBJECTIVE(S): To systematically review literature on brief screening tools used to detect and differentiate between normal cognition and neurocognitive impairment and HIV-associated neurocognitive disorders (HANDs) in adult populations of persons...

Weighing the gold in the gold standard: Challenges in HIV prevention research

2010

OBJECTIVE(S): Few HIV prevention interventions have been evaluated in randomized controlled trials (RCTs). We examined design, implementation, and contextual considerations that may limit detection of a positive or adverse effect...

HIV infection and the fronto-striatal system: A systematic review and meta-analysis of fMRI studies

2014

Functional MRI studies investigating the impact HIV on the brain have implicated the involvement of fronto-striatal circuitry. However, to date there is no review and meta-analysis of this work. We...

Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and susceptibility to HIV-1 infection: A meta-analysis

2013

BACKGROUND: Many studies have investigated the distributions of RANTES genotypes between HIV-1 infected patients and uninfected individuals. However, no definite results have been put forward about whether the RANTES -28C/G...

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