Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Systemic preexposure prophylaxis for HIV: Translating clinical data to clinical practice
OBJECTIVE: To assess the real-world implications of oral tenofovir-emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. DATA SOURCES: A search of...
A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: Rethinking the significance of serological non-responsiveness and the serofast state after therapy
BACKGROUND: Syphilis remains a global public health threat and can lead to severe complications. In addition to resolution of clinical manifestations, a reduction in nontreponemal antibody titers after treatment is...
Investments in sexually transmitted infection research, 1997-2013: A systematic analysis of funding awarded to UK institutions
BACKGROUND: We report the first study that analyses public and philanthropic investments awarded to UK institutions for research related to sexually transmitted infections (STIs). METHODS: We systematically searched award data...
Provider-initiated HIV testing and counseling in low- and middle-income countries: A systematic review
Provider-initiated HIV testing and counseling (PITC) has expanded since 2007 WHO guidelines were established. We conducted a systematic review of PITC in low- and middle-income countries. Peer-reviewed studies were included...
Effectiveness of ART and condom use for prevention of sexual HIV transmission in serodiscordant couples: A systematic review and meta-analysis
BACKGROUND: Consistent and correct condom use and suppressive antiretroviral therapy for the infected partner are two of the primary strategies recommended for prevention of heterosexual HIV transmission in serodiscordant couples...
TRIM5alpha H43Y polymorphism and susceptibility to HIV-1 infection: A meta-analysis
TRIM5alpha is an antiviral factor that can greatly limit HIV-1 infection. Although several researchers have investigated whether TRIM5alpha H43Y polymorphism influences the risk of HIV-1 infection, no definite conclusion has...
HIV seroconversion and prevalence rates in heterosexual discordant couples in China: A systematic review and meta-analysis
This study aims to systematically review published literature on heterosexual transmission among HIV discordant couples in China. We conducted a systematic review and random-effects meta-analysis of 32 published articles in...
Considerations for implementing oral preexposure prophylaxis: A literature review
Oral preexposure prophylaxis (PrEP) is in its infancy as an approved biomedical intervention; therefore, research is needed to understand the issues surrounding its implementation. The purpose of this literature review...
