Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: Results of a systematic overview
BACKGROUND: Many trials of antiretroviral therapy in treatment-naïve subjects have investigated the relative efficacy of the third drug in a treatment regimen. However, the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) components...
Mortality rates in people dually infected with HIV-1/2 and those infected with either HIV-1 or HIV-2: a systematic review and meta-analysis
OBJECTIVE:: As compared to HIV-1 infection, HIV-2 is less transmissible, disease progression is slower, and the mortality risk is lower. It has been suggested that HIV-2 infection inhibits the progression...
No association of abacavir use with myocardial infarction: Findings of an FDA meta-analysis
BACKGROUND: Several studies have reported an association between abacavir (ABC) exposure and increased risk of myocardial infarction (MI) among HIV-infected individuals. Randomized controlled trials (RCTs) and a pooled analysis by...
Effectiveness of peer education interventions for HIV prevention in developing countries: A systematic review and meta-analysis
Peer education for HIV prevention has been widely implemented in developing countries, yet the effectiveness of this intervention has not been systematically evaluated. We conducted a systematic review and meta-analysis...
Polymerase chain reaction for the diagnosis of HIV infection in adults: A meta-analysis with recommendations for clinical practice and study design
PURPOSE: To do a meta-analysis of studies that have evaluated the sensitivity and specificity of polymerase chain reaction (PCR) assay for the diagnosis of human immunodeficiency virus (HIV) infection in...
Syphilitic uveitis: A review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients
The incidence of syphilis and syphilitic uveitis in our community is increasing. The prevalence of associated neurosyphilis is unknown, and it remains unclear whether syphilitic uveitis should be treated as...
HIV seroconversion and prevalence rates in heterosexual discordant couples in China: A systematic review and meta-analysis
This study aims to systematically review published literature on heterosexual transmission among HIV discordant couples in China. We conducted a systematic review and random-effects meta-analysis of 32 published articles in...
Considerations for implementing oral preexposure prophylaxis: A literature review
Oral preexposure prophylaxis (PrEP) is in its infancy as an approved biomedical intervention; therefore, research is needed to understand the issues surrounding its implementation. The purpose of this literature review...
A systematic review of strategies for partner notification for sexually transmitted diseases including HIV/AIDS
This review compares the effects of various sexually transmitted disease (STD) partner-notification strategies. Using review methods endorsed by the Cochrane Collaboration, it updates previous reviews, and addresses some of their...
The validity of the modification of diet in renal disease formula in HIV-infected patients: A systematic review
RATIONALE, AIMS AND OBJECTIVES: Renal dysfunction is highly prevalent in HIV-infected patients and may require dose adjustment of renally excreted antiretroviral drugs. The Modification of Diet in Renal Disease (MDRD)-4...
