Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Mortality rates in people dually infected with HIV-1/2 and those infected with either HIV-1 or HIV-2: a systematic review and meta-analysis
OBJECTIVE:: As compared to HIV-1 infection, HIV-2 is less transmissible, disease progression is slower, and the mortality risk is lower. It has been suggested that HIV-2 infection inhibits the progression...
Comparative efficacy of nucleoside/nucleotide reverse transcriptase inhibitors in combination with efavirenz: Results of a systematic overview
BACKGROUND: Many trials of antiretroviral therapy in treatment-naïve subjects have investigated the relative efficacy of the third drug in a treatment regimen. However, the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) components...
A systematic review of the effects of different types of therapeutic exercise on physiologic and functional measurements in patients with HIV/AIDS
Several studies have reported the benefits of exercise training for adults with HIV, although there is no consensus regarding the most efficient modalities. The aim of this study was to...
Efficacy and safety of micafungin for invasive candida infections: A meta-analysis of randomized controlled trials
Background Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most...
The impact of HIV treatment as prevention in the presence of other prevention strategies: Lessons learned from a review of mathematical models set in resource-rich countries
OBJECTIVE: We aimed to assess the potential prevention benefits of HIV treatment as prevention (TasP) in resource-rich countries and examine the potential interactions between TasP and other prevention strategies by...
Weighing the gold in the gold standard: Challenges in HIV prevention research
OBJECTIVE(S): Few HIV prevention interventions have been evaluated in randomized controlled trials (RCTs). We examined design, implementation, and contextual considerations that may limit detection of a positive or adverse effect...
Factors influencing adherence in Hepatitis-C infected patients: A systematic review
BACKGROUND: Adherence is a crucial point for the successful treatment of a hepatitis-C virus infection. Studies have shown that especially adherence to ribavirin is important.The objective of this systematic review...
The prevalence of sexually transmitted infections in Papua New Guinea: A systematic review and meta-analysis
BACKGROUND: The potential for an expanded HIV epidemic in Papua New Guinea (PNG) demands an effective, evidence-based and locally-appropriate national response. As sexually transmitted infections (STIs) may be important co-factors...
The validity of the modification of diet in renal disease formula in HIV-infected patients: A systematic review
RATIONALE, AIMS AND OBJECTIVES: Renal dysfunction is highly prevalent in HIV-infected patients and may require dose adjustment of renally excreted antiretroviral drugs. The Modification of Diet in Renal Disease (MDRD)-4...
