Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Suppression of HBV by tenofovir in HBV/HIV coinfected patients: A systematic review and meta-analysis.
BACKGROUND: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available...
Cost-effectiveness of adherence interventions for highly active antiretroviral therapy: A systematic review
Objectives: The objective of this systematic review was to evaluate the cost-effectiveness of interventions aiming to increase the adherence to highly active antiretroviral therapy (HAART) in HIV-infected patients in developed...
Impact of baseline HIV-1 RNA levels on initial highly active antiretroviral therapy outcome: A meta-analysis of 12,370 patients in 21 clinical trials
BACKGROUND: Individual randomized trials of first-line antiretroviral treatment do not consistently show an association between higher baseline HIV-1 RNA and lower efficacy. METHODS: A MEDLINE search identified 21 HIV clinical...
Fixed-dose combinations improve medication compliance: A meta-analysis
BACKGROUND: Compliance with treatment is a sine qua non for successful treatment of chronic conditions like hypertension. Fixed-dose combinations are designed to simplify the medication regimen and potentially improve compliance....
Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults
AIM: To estimate the effectiveness of triple combination therapy in antiretroviral-naive adults. METHODS: A systematic overview of results from clinical trials involving triple combination therapy with dual nucleoside reverse transcriptase...
Evaluation of STD/AIDS prevention programs: A review of approaches and methodologies
The article presents a review of approaches and methodologies in the evaluation of STD/AIDS prevention programs, searching for theoretical and methodological support for the institutionalization of evaluation and decision-making. The...
Persuasive communications to change actions: An analysis of behavioral and cognitive impact in HIV prevention
This meta-analysis examined the validity of various theoretical assumptions about cognitive and behavioral change following a communication recommending condom use. The synthesis comprised 82 treatment and 29 control groups included...
Analytic review of modeling studies of ARV Based PrEP interventions reveals strong influence of drug-resistance assumptions on the population-level effectiveness
BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and...
Economic costs of HIV/AIDS prevention activities in sub-Saharan Africa
This paper reviews the existing evidence base of the costs of prevention activities in sub-Saharan Africa, considers the degree of comparability between different cost estimates and highlights factors that are important in attempting...
