Category Archives: General HIV- population
Reviews on HIV- people that explore topics including risk, screening, and prevention
Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence
Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...
Effects of Digital Health Interventions to Promote Safer Sex Behaviors Among Youth: Systematic Review and Bayesian Network Meta-Analysis
BACKGROUND: Youth aged 15-24 years carry a disproportionate HIV/sexually transmitted infections (STIs) burden. In recent years, different modalities of digital health interventions (DHIs) have been explored to promote safer sex...
Doxycycline prophylaxis is effective as pre-exposure and post-exposure regimens in the prevention of sexually transmitted infections: An updated systematic review and meta-analysis
BACKGROUND: Recent systematic reviews have demonstrated the efficacy of doxycycline prophylaxis in preventing bacterial sexually transmitted infections (STIs)Aÿin randomised controlled trials (RCTs). In this review, we updated evidence from RCTs...
Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: a scoping review
BACKGROUND: HIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including Uƒ_%=ƒ_%U (Undetectableƒ_%=ƒ_%Untransmittable). Effective interventions are crucial to support these...
Colliding Wars: A Systematic Review on HIV Responses in Conflict-Affected Settings
BACKGROUND: Armed conflicts are an escalating threat to public health, often marked by violence, poverty, displacement and weakened health systems-conditions that mirror the drivers of HIV transmission. AIM: This review...
HIV self-testing and clinician-administered testing in Southern Africa: A systematic review of programmatic outcomes
OBJECTIVE: In 2024, an estimated 5.3 million of 40.8 million people with HIV (PWH) globally were unaware of their status, with Southern Africa bearing the highest regional burden. This review...
Person-centred HIV prevention services in sub-Saharan Africa: A scoping review
BACKGROUND: In spite of numerous advancements in HIV prevention, there are still gaps that impede reaching key populations throughout sub-Saharan Africa. Traditional approaches usually overlook personal preferences, social context and...
Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: A systematic review
Introduction Tuberculosis is a leading infectious cause of death and morbidity in people with and without HIV. Better identification of severe forms could help target early interventions to reduce mortality...
Systematic review and meta-analysis of respiratory virus infections in HIV-positive and HIV-negative patients
BACKGROUND: Respiratory virus infections are a major cause of morbidity and mortality globally, particularly among people living with HIV. OBJECTIVES: To evaluate the impact of respiratory virus infections on clinical...
PrEP delivery for US adolescents and young adults: A systematic review and narrative synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review
INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...
