Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV
Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking....
Dolutegravir + lamivudine effectiveness and tolerability in real-world cohorts with HIV-1 across Asia and South America: A systematic literature review
Background: Dolutegravir (DTG) + lamivudine (3TC) has demonstrated efficacy and safety in phase 3 clinical trials; however, most published data are from people with HIV-1 in North America and Europe. Methods: To...
Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review
Background Antiretroviral (ARV) exposure influences the early-life gut microbiota in regions with high human immunodeficiency virus (HIV) burdens. Understanding how ARV drugs affect the infant gut microbiota is important for...
Evaluating the impact of COVID-19 on the HIV care continuum across global income levels: A mixed-methods systematic review
BACKGROUND: The COVID-19 pandemic caused significant disruptions to global healthcare systems, including essential services along the HIV care continuum (HCC). While several studies have examined these impacts in specific countries...
Psychosocial experience and coping of AIDS patients about the disease: A systematic review and qualitative meta-synthesis
AIM: To systematically integrate the psychosocial experiences and coping mechanisms of AIDS patients after the disease, and to understand their true feelings, in order to provide a basis for better...
Reducing HIV risk behaviors among Black women living with and without HIV/AIDS in the U.S.: A systematic review
This systematic review provides an examination of the status of HIV/AIDS prevention interventions for Black, heterosexual women in the U.S. from 2012 to 2019. Using PRISMA guidelines, 28 interventions were...
Efficacy and safety of echinocandins combined with Trimethoprim-Sulfamethoxazole as first-line treatment for Pneumocystis pneumonia in HIV-infected and non-HIV-infected patients
Introduction Pneumocystis pneumonia (PCP) is a life-threatening infection in both HIV- infected and non-HIV-infected immunocompromised patients. Although Trimethoprim-Sulfamethoxazole (TMP/SMX) combined with echinocandins has been used clinically, whether this combination is...
Mortality and associated factors among children with the double burden of human immunodeficiency virus and tuberculosis in African countries: A systematic review and meta-analysis
Introduction The dual burden of Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) in children is leading to significant mortality. Although primary studies have reported wide ranges of mortality rates among...
Possible prevention of neurodevelopmental consequences of vertical HIV transmission in early childhood? A systematic review
BACKGROUND: Children infected with the Human Immunodeficiency Virus (HIV) exhibit the lowest neurodevelopmental scores. Mother-to-child-transmission prevention include perinatally and early antiretroviral therapy (ART) although long-term effects of in utero exposure...
Syndemic interactions between HIV/AIDS, mental health conditions, and non-communicable diseases in sub-Saharan Africa: A scoping review of contributing factors
INTRODUCTION: The syndemic framework provides a critical lens for understanding the complex interplay between HIV/AIDS, mental health (MH) conditions, and non-communicable diseases (NCDs) in Africa. This scoping review explores how...
Acceptability, needs, concerns, and barriers to digital-based interventions for the prevention of mother-to-child transmission of HIV: Systematic review and qualitative meta-aggregation
BACKGROUND: Digital-based interventions have the potential to support initiatives for the prevention of mother-to-child HIV transmission (PMTCT). Nevertheless, reviews to explore experiences and perspectives toward digital-based interventions in mothers living...
Social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV: A scoping review
OBJECTIVE: To map scientific evidence related to social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV. METHOD: Scoping review according to JBI methodology, carried...
