Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV
Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking....
Dolutegravir + lamivudine effectiveness and tolerability in real-world cohorts with HIV-1 across Asia and South America: A systematic literature review
Background: Dolutegravir (DTG) + lamivudine (3TC) has demonstrated efficacy and safety in phase 3 clinical trials; however, most published data are from people with HIV-1 in North America and Europe. Methods: To...
Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review
Background Antiretroviral (ARV) exposure influences the early-life gut microbiota in regions with high human immunodeficiency virus (HIV) burdens. Understanding how ARV drugs affect the infant gut microbiota is important for...
Evaluating the impact of COVID-19 on the HIV care continuum across global income levels: A mixed-methods systematic review
BACKGROUND: The COVID-19 pandemic caused significant disruptions to global healthcare systems, including essential services along the HIV care continuum (HCC). While several studies have examined these impacts in specific countries...
Psychosocial experience and coping of AIDS patients about the disease: A systematic review and qualitative meta-synthesis
AIM: To systematically integrate the psychosocial experiences and coping mechanisms of AIDS patients after the disease, and to understand their true feelings, in order to provide a basis for better...
Reducing HIV risk behaviors among Black women living with and without HIV/AIDS in the U.S.: A systematic review
This systematic review provides an examination of the status of HIV/AIDS prevention interventions for Black, heterosexual women in the U.S. from 2012 to 2019. Using PRISMA guidelines, 28 interventions were...
Strategies for improving linkage to HIV care after hospital discharge among adults living with HIV in low- and middle-income countries: A systematic review
Purpose Despite the availability of antiretroviral therapy (ART), nearly a quarter of people living with HIV (PLHIV) die within six months after hospital discharge due to complications from AIDS-related illnesses....
Evidence-based interventions targeting mental health problems in adolescents living with HIV: A scoping review
Adolescents living with HIV are at an increased risk of experiencing mental health challenges, impacting their overall well-being and treatment adherence. Evidence-based interventions are crucial to addressing these issues; however,...
Efficacy and safety of echinocandins combined with Trimethoprim-Sulfamethoxazole as first-line treatment for Pneumocystis pneumonia in HIV-infected and non-HIV-infected patients
Introduction Pneumocystis pneumonia (PCP) is a life-threatening infection in both HIV- infected and non-HIV-infected immunocompromised patients. Although Trimethoprim-Sulfamethoxazole (TMP/SMX) combined with echinocandins has been used clinically, whether this combination is...
Mortality and associated factors among children with the double burden of human immunodeficiency virus and tuberculosis in African countries: A systematic review and meta-analysis
Introduction The dual burden of Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) in children is leading to significant mortality. Although primary studies have reported wide ranges of mortality rates among...
Possible prevention of neurodevelopmental consequences of vertical HIV transmission in early childhood? A systematic review
BACKGROUND: Children infected with the Human Immunodeficiency Virus (HIV) exhibit the lowest neurodevelopmental scores. Mother-to-child-transmission prevention include perinatally and early antiretroviral therapy (ART) although long-term effects of in utero exposure...
