Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-Infected adults: A systematic review and meta-analysis
Background: The HIV associated mortality is decreasing in most countries due to the widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder (HAND) remains a problematic issue that lowers the...
Impact of COVID-19 in patients with concurrent co-infections: A systematic review and meta-analyses
The burden and impact of secondary superadded infections in critically ill coronavirus disease 2019 (COVID-19) patients is widely acknowledged. However, there is a dearth of information regarding the impact of...
Potential risk factors associated with seropositivity for Toxoplasma gondii among pregnant women and HIV infected individuals in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Toxoplasma gondii is an obligate intracellular and neurotropic apicomplexan protozoan parasite infecting almost all warm-blooded vertebrates including humans. To date in Ethiopia, no systematic study has been investigated on...
Eliciting Preferences for HIV Prevention Technologies: A Systematic Review
BACKGROUND: Many human immunodeficiency virus (HIV) prevention technologies (pre-exposure prophylaxis, microbicides, vaccines) are available or in development. Preference elicitation methods provide insight into client preferences that may be used to...
Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource-poor settings: A systematic review and metaanalysis
BACKGROUND: Despite the increase in the number of people accessing antiretroviral therapy (ART), there is limited data regarding treatment failure and its related factors among HIV-positive individuals enrolled in HIV...
Immunogenicity of pneumococcal vaccination in HIV infected individuals: A systematic review and meta-analysis
Background: The objective of this systematic review and meta-analysis was to summarise the literature regarding the immunogenicity of pneumococcal conjugate vaccines (PCV) and pneumococcal polysaccharide vaccines (PPSV) in adult people...
Comparative efficacy, tolerability and safety of dolutegravir and efavirenz 400mg among antiretroviral therapies for first-line HIV treatment: A systematic literature review and network meta-analysis
Background: To inform World Health Organization (WHO) global guidelines, we updated and expanded the evidence base to assess the comparative efficacy, tolerability, and safety of first-line antiretroviral therapy (ART) regimens....
The effect of probiotics, prebiotics, and synbiotics on cd4 counts in HIV-infected patients: A systematic review and meta-analysis
BACKGROUND: Probiotics as a potential adjuvant therapy may improve the restoration of the intestinal CD4(+) T-cell population in HIV-infected patients, whereas findings from clinical trials are inconsistent. This systematic review...
A meta-analysis of different types of cardiac adipose tissue in HIV patients
BACKGROUND: Antiretroviral therapy transformed HIV infection into a chronic disease but accelerated cardiovascular disease (CVD). Both of epicardial adipose tissue (EAT) and pericardial fat (PCF) have close relationships with CVD....
Prevalence of pretreatment HIV drug resistance in key populations: A systematic review and meta-analysis
Introduction: WHO’s 2019 report on HIV drug resistance (HIVDR) documents a high prevalence of pretreatment drug resistance (PDR) among populations initiating first-line antiretroviral therapy (ART) in low- and middle-income countries...
Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: A narrative overview
BACKGROUND: South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may...
