Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Risk factors for loss to follow-up from antiretroviral therapy programmes in low-income and middle-income countries
Introduction: Loss to follow-up (LTFU) rates from antiretroviral treatment (ART) programmes in low- and middle-income countries (LMIC) are high, leading to poor treatment outcomes and onward transmission of HIV. Knowledge of...
Strategies for retention of heterosexual men in HIV care in sub-Saharan Africa: A systematic review
Expansion of Antiretroviral Therapy (ART) programs in sub-Saharan Africa (SSA) has increased the number of people accessing treatment. However, the number of males accessing and being retained along the human...
Structural interventions for HIV prevention and care among US men who have sex with men: A systematic review of evidence, gaps, and future priorities
The preponderance of HIV interventions have been behavioral, targeting individual, dyadic, or group dynamics. However, structural-level interventions are required to decrease HIV transmission and increase engagement in care, especially for...
Effectiveness and safety of dolutegravir two-drug regimens in virologically suppressed people living with HIV: A systematic literature review and meta-analysis of real-world evidence
Objectives: Dolutegravir (DTG) is widely recommended within three-drug regimens. However, similar efficacy and tolerability have also been achieved with DTG within two-drug regimens in clinical trials. This study evaluated the real-world...
Impact of antiretroviral therapy on cancer treatment outcomes among people living with HIV in low- and middle-income countries: A systematic review
PURPOSE OF REVIEW: The relationship between antiretroviral therapy (ART) and cancer treatment outcomes among people living with HIV (PLWH) in low- and middle-income countries (LMICs) is complex and poorly understood...
A systematic review of early adoption of implementation science for HIV prevention or treatment in the United States
OBJECTIVE: To provide the first systematic review of the early adoption of implementation science for HIV prevention or treatment in the United States. We identified primary research studies that addressed...
The impact of antiretroviral therapy on neurocognitive outcomes among people living with HIV in low- and middle-income countries (LMICs): A systematic review
Low and middle-income countries (LMICs) are the epicenter of the HIV epidemic. The scale-up of antiretroviral therapy (ART) has reduced mortality, but HIV-associated neurocognitive impairment (HANI) remains prevalent, which impacts...
A systematic review and meta-analysis of telephone-based therapy targeting depressive symptoms among low-income people living with HIV
People living with human immunodeficiency virus (PLWH) has been reported to have a high prevalence of depressive symptoms. Low-income populations account for a large proportion of PLWH, hence indicating a...
Evidence regarding rapid initiation of antiretroviral therapy in patients living with HIV
PURPOSE OF REVIEW: Rapid initiation of antiretroviral therapy (ART) is increasingly more common among clinics serving people living with human immunodeficiency virus (PLWH). It is recommended by major guidelines and...
Global burden of active smoking among people living with HIV on antiretroviral therapy: A systematic review and meta-analysis
Background: Although the high burden of both active smoking and human immunodeficiency virus (HIV) is clearly known, the relationship between them is still not well characterized. Therefore, we estimated the...
The prevalence of laboratory-confirmed Pneumocystis jirovecii in HIV-infected adults in Africa: A systematic review and meta-analysis
BACKGROUND: The epidemiology of Pneumocystis jirovecii, known to colonize the respiratory tract and cause a life-threatening HIV-associated pneumonia (PCP), is poorly described in Africa. We conducted a systematic review to...
Dangerous liaisons? The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection
INTRODUCTION: In people living with HIV (PLWH), immune activation and inflammation levels are high even when viral suppression is maintained, potentially contributing to several comorbidities, and hampering the immune response...
