Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
The pharmacogenetics of efavirenz metabolism in children: The potential genetic and medical contributions to child development in the context of long-term ARV treatment
Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between...
Cryptococcal meningitis: A review of cryptococcal antigen screening programs in Africa
INTRODUCTION: Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis....
Factors associated with injecting-related risk behaviors among people who inject drugs: A systematic review and meta-analysis study
We conducted this systematic review and meta-analysis study to better understand the factors (being drug use, drug type (methamphetamine vs others), sex partner, frequency of injection, homelessness and being HIV...
Characteristics of successful programmes targeting gender inequality and restrictive gender norms for the health and wellbeing of children, adolescents, and young adults: A systematic review
BACKGROUND: In the context of the Sustainable Development Goals and the shifting global burden of disease, this systematic review analyses the evidence from rigorously evaluated programmes that seek to transform...
Tuberculosis and its association with CD4(+) T cell count among adult HIV positive patients in Ethiopian settings: A systematic review and meta-analysis
BACKGROUND: Tuberculosis (TB) and HV have been intertwined and makeup a deadly human syndemic worldwide, especially in developing countries like Ethiopia. Previous studies have reported different TB incidences and its...
impact of pre-antiretroviral therapy CD4 counts on drug resistance and treatment failure: A systematic review
The continuous rising of HIV drug resistance in low- and middle-income countries and its impact on treatment failure is a growing threat for the HIV treatment response. This review aimed...
Global burden of hypertension among people living with HIV in the era of increased life expectancy: A systematic review and meta-analysis
BACKGROUND: Although HIV infection and antiretroviral therapy (ART) increase the risk for hypertension in people living with HIV (PLHIV), the global and regional burden of hypertension in PLHIV is not...
Ventriculoperitoneal shunt insertion in human immunodeficiency virus infected adults: A systematic review and meta-analysis
BACKGROUND: Hydrocephalus is a common, life threatening complication of human immunodeficiency virus (HIV)-related central nervous system opportunistic infection which can be treated by insertion of a ventriculoperitoneal shunt (VPS). In...
Two’s a company, three’s a crowd: A review of initiating or switching to a two-drug antiretroviral regimen in treatment-naive and treatment-experienced patients living with HIV-1
INTRODUCTION: As HIV has become a manageable chronic condition, a renewed and increased interest in challenging traditional three-drug HIV therapies and moving toward two-drug regimens (2DR) for initial or maintenance...
A systematic review of mobile phone interventions (SMS/IVR/Calls) to improve adherence and retention to antiretroviral treatment in low-and middle-income countries
The use of mobile health technologies (mHealth) to ameliorate HIV care has considerably risen in low- and middle-income countries (LMICs) since 2010. Yet, the discrepancies in the results of accompanying...
