Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Psychosocial and behavioural interventions towards HIV risk reduction for serodiscordant couples in Africa: A systematic review
Background: Sexual transmission of HIV frequently occurs in the context of a primary relationship between two partners; however, HIV prevention interventions generally focus on individuals at risk, rather than specifying...
Psychosocial factors associated with persistent pain in people with HIV: A systematic review with meta-analysis
Chronic pain remains a prevalent and disabling problem for people living with the human immunodeficiency virus (HIV) in the current antiretroviral (ART) treatment era. Psychosocial treatments may have promise for...
The effects of viral load and antiretroviral medications on sexual transmission of HIV
Key take-home messages Several studies have noted differences in viral load levels when comparing blood plasma to semen, cervicovaginal secretions and rectal mucosa. Despite an undetectable blood plasma viral load...
A systematic review of the efficacy and safety of fecal microbiota transplant for clostridium difficile infection in immunocompromised patients
Background: Fecal microbiota transplantation (FMT) has been shown to be effective in recurrent Clostridium difficile (CD) infection, with resolution in 80% to 90% of patients. However, immunosuppressed patients were often...
Sensitivity and specificity of WHO’s recommended four-symptom screening rule for tuberculosis in people living with HIV: A systematic review and meta-analysis
BACKGROUND: Since 2011, WHO recommends a four-symptom screening rule to exclude active tuberculosis in people living with HIV before starting tuberculosis preventive treatment (ie, absence of current cough, weight loss,...
Risk of cardiovascular disease associated with exposure to abacavir among individuals with HIV: A systematic review and meta-analyses of results from seventeen epidemiologic studies
BACKGROUND: Abacavir’s potential to cause cardiovascular disease (CVD) among people living with HIV (PLWH) is debated. We conduct a systematic review and meta-analyses to assess CVD risk from recent and...
Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: A systematic review and meta-analysis
OBJECTIVE: To appropriately identify and treat noncommunicable diseases (NCDs) among persons living with HIV (PLHIV) in low-and-middle-income countries (LMICs), it is imperative to understand the burden of NCDs among PLHIV...
Increased risk of aminoglycoside-induced hearing loss in MDR-TB patients with HIV coinfection
SETTING: A high proportion of individuals with multidrug-resistant tuberculosis (MDR-TB) develop permanent hearing loss due to ototoxicity caused by injectable aminoglycosides (AGs). The prevalence of AG-induced hearing loss is greatest...
