Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Epidemiology of Chlamydia trachomatis in the Middle East and North Africa: A systematic review, meta-analysis, and meta-regression
BACKGROUND: The epidemiology of Chlamydia trachomatis in the Middle East and north Africa is poorly understood. We aimed to provide a comprehensive epidemiological assessment of C trachomatis infection in the...
Immunological efficacy of Tenofovir disproxil fumarate-containing regimens in Patients With HIV-HBV coinfection: A systematic review and meta-analysis
Background: Hepatitis B virus (HBV) coinfection is common in HIV-positive patients. HIV infection modifies the natural course of HBV infection, leading to a faster progression of liver-related morbidity and mortality...
HIV testing barriers and intervention strategies among men, transgender women, female sex workers and incarcerated persons in the Caribbean: A systematic review
BACKGROUND: This systematic review summarises evidence on the HIV testing barriers and intervention strategies among Caribbean populations and provides pertinent implications for future research endeavours designed to increase rates of...
Meta-analysis and systematic review of the efficacy and resistance for human immunodeficiency virus type 1 integrase strand transfer inhibitors
Integrase strand transfer inhibitors (INSTIs) are the most recent class of antiretroviral drugs with potent and durable antiviral activity used to treat human immunodeficiency virus type 1 (HIV-1) infection. However,...
Prevalence of HIV-seropositivity and associated impact on mortality among injured patients from low-and middle-income countries: A systematic review and meta-analysis
BACKGROUND: Although HIV and injury contribute substantially to disease burdens in low-and middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE: This systematic review assessed the prevalence and associated mortality...
Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors
BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...
Dolutegravir based antiretroviral therapy compared to other combined antiretroviral regimens for the treatment of HIV-infected naive patients: A systematic review and meta-analysis
BACKGROUND: Numerous randomized clinical trials (RCTs) were conducted to evaluate dolutegravir based triple antiretroviral therapy (ART) compared to other triple antiretroviral regimens in naive patients, and a summary of the...
Necessity and concerns beliefs and HIV medication adherence: A systematic review
According to the Necessity-Concerns Framework, beliefs about medication necessity and concerns are two core themes from diverse patient medication beliefs across chronic illnesses that may directly influence adherence. Past work...
Virologically suppressed HIV-infected patients on TDF-containing regimens significantly benefit from switching to TAF-containing regimens: A meta-analysis of randomized controlled trials
BACKGROUND: To investigate whether TDF-containing regimens significantly benefited efficacy, safety, and tolerability in TAF-containing regimens in virologically suppressed HIV-infected patients. METHODS: PubMed, Embase, Web of Science, and the Cochrane T
Which community-based HIV initiatives are effective in achieving UNAIDS 90-90-90 targets? A systematic review and meta-analysis of evidence (2007-2018)
BACKGROUND: Reaching the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets to end the HIV epidemic relies on effective interventions that engage untested HIV+ individuals and retain them in...
