Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Single-session behavioral interventions for sexual risk reduction: A meta-analysis
BACKGROUND: Evidence-based, single-session STI/HIV interventions to reduce sexual risk taking are potentially effective options for implementation in resource-limited settings and may solve problems associated with poor participant retention. PURPOSE: The...
Which aspects of health care are most valued by people living with HIV in high-income countries? A systematic review
BACKGROUND: Increasing numbers of people with HIV are living into older age and experiencing comorbidities. The development of new models of care to meet the needs of this population is...
Transactional sex and risk for HIV infection in sub-Saharan Africa: A systematic review and meta-analysis
INTRODUCTION: Young women aged 15 to 24 years in sub-Saharan Africa continue to be disproportionately affected by HIV. A growing number of studies have suggested that the practice of transactional...
Association between immune markers and surrogate markers of cardiovascular disease in HIV positive patients: A systematic review
BACKGROUND: HIV infection is associated with an increased risk of cardiovascular disease (CVD). Chronic low-grade immune activation is likely one of the driving mechanisms. This systematic review provides an overview...
Respiratory symptoms in people living with HIV and the effect of antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Antiretroviral therapy (ART) has significantly altered the pattern of acute and chronic HIV-related disease. However, it is not clear what this means in terms of respiratory symptoms. We sought...
Patient-reported barriers to adherence to antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Maintaining high levels of adherence to antiretroviral therapy (ART) is a challenge across settings and populations. Understanding the relative importance of different barriers to adherence will help inform the...
Resourcing resilience: social protection for HIV prevention amongst children and adolescents in Eastern and Southern Africa
Adolescents are the only age group with growing AIDS-related morbidity and mortality in Eastern and Southern Africa, making HIV prevention research among this population an urgent priority. Structural deprivations are...
Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: Systematic review and meta-analysis
Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy...
Diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome patients with intracranial lesions: Systematic review and meta-analysis
OBJECTIVE: To evaluate the diagnostic value and safety of stereotactic biopsy in acquired immune deficiency syndrome (AIDS) patients with intracranial lesions via meta-analysis. METHODS: Relevant cohort studies were identified through...
Clostridium difficile: A healthcare-associated infection of unknown significance in adults in sub-Saharan Africa
BACKGROUND: Clostridium difficile infection (CDI) causes a high burden of disease in high-resource healthcare systems, with significant morbidity, mortality, and financial implications. CDI is a healthcare-associated infection for which the...