Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of “Universal Test and Treat”: A systematic review and meta-analysis
INTRODUCTION: The “Universal Test and Treat” (UTT) era for antiretroviral therapy (ART) increased HIV service delivery to children and adolescents aged 0-19 with HIV. The goal is to reach %95%...
Free antiretrovirals as a key tool against the HIV pandemic: A systematic review
BACKGROUND/OBJECTIVES: Access to antiretroviral (ARV) drugs remains a critical challenge in achieving the WHO/UNAIDS 95-95-95 targets, with medication costs representing a substantial barrier. This systematic review evaluates the effect of...
Cabotegravir plus rilpivirine injection for virally suppressed persons with HIV-1 infection: A systematic review and meta-analysis of randomized controlled trials
Purpose: This study evaluated the efficacy and safety of cabotegravir/rilpivirine long-acting formulation compared to oral standard of care at 48 and 52 weeks. Method: We conducted an electronic search (2005-2024) across databases...
Evaluating the safety and efficacy of malaria preventive measures in pregnant women with a focus on HIV status: A systematic review and network meta-analysis
Background and Objectives: Malaria poses significant threats to pregnant women, particularly in endemic regions. Preventive measures against it include insecticide-treated bed nets, intermittent preventive treatment, and various supplements. We aimed...
Pharmacokinetic adaptations in pregnancy: Implications for optimizing antiretroviral therapy in HIV-positive women
Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining...
Global research landscape of HIV and Kaposi’s sarcoma: A visualized bibliometric analysis
BACKGROUND: Human immunodeficiency virus (HIV) infection remains a significant global health challenge, with Kaposi’s sarcoma (KS) being one of the most common AIDS-defining cancers. This study aimed to investigate the...
Efficacy and safety of systematic corticosteroids treatment among patients with HIV and tuberculosis: A systematic review and meta-analysis of randomized controlled trials
INTRODUCTION: The efficacy and safety of corticosteroids in patients with human immunodeficiency virus (HIV) and tuberculosis (TB) remain controversial. METHOD: PubMed, Embase, Web of Science, and the Cochrane Database were...
Prevalence of HIV drug resistance among patients experiencing first-line treatment failure in Ethiopia: A systematic review and meta-analysis
Background The emergence of human immunodefiency virus (HIV) drug resistance presents a substantial challenge. Alternatives for effective treatment regimens are limited, and treatment strategies are complicated. Although a number of...
Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis
People living with HIV (PLHIV) often require antifungal medications for the treatment or prevention of infections, which may contribute to the emergence of resistant Candida albicans strains. This systematic review...
