Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
A meta-analysis of the performance of the Pima CD4 for point of care testing
BACKGROUND: The Alere point-of-care (POC) Pima CD4 analyzer allows for decentralized testing and expansion to testing antiretroviral therapy (ART) eligibility. A consortium conducted a pooled multi-data technical performance analysis of...
Basis of selection of first and second line highly active antiretroviral therapy for HIV/AIDS on genetic barrier to resistance: A literature review
Long-term management of HIV/AIDS is at risk of increasing drug resistance1. Booster protease inhibitor (PI) and thymidine analogue-containing regimens have a high genetic barrier to resistance. Non-thymidine-analogue triple nucleoside/nucleotide reverse...
Are there differences in disease progression and mortality among male and female HIV patients on antiretroviral therapy? A meta-analysis of observational cohorts
Studies examining the sex differences in morbidity and mortality among HIV/AIDS patients have yielded inconsistent results. We conducted a meta-analysis of sex differences in disease progression and mortality among HIV/AIDS...
Effects of HIV antiretroviral therapy on sexual and injecting risk-taking behavior: A systematic review and meta-analysis.
BACKGROUND: Increased global access and use of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by changing individual risk-taking behavior. This review...
Initial highly-active antiretroviral therapy with a protease inhibitor versus a non-nucleoside reverse transcriptase inhibitor: Discrepancies between direct and indirect meta-analyses
BACKGROUND: The optimum treatment choice between initial highly-active antiretroviral therapy (HAART) with a protease inhibitor (PI) versus a non-nucleoside reverse transcriptase inhibitor (NNRTI) is uncertain. An indirect analysis reported that...
A comparative systematic review of the optimal CD4 cell count threshold for HIV treatment initiation
HIV infection is no longer characterized by high morbidity, rapid progression to AIDS, and death as when the infection was first identified. While anti-retroviral drugs have improved the outcome of...
The prevalence of HIV-1 drug resistance among antiretroviral treatment naïve individuals in mainland China: A meta-analysis
BACKGROUND: Surveillance of drug resistance in antiretroviral treatment-naive patients in China is needed to ensure optimal treatment outcomes and control of the human immunodeficiency virus (HIV) epidemic. METHODS: A systematic...
Diagnosing acute and prevalent HIV-1 infection in young African adults seeking care for fever: A systematic review and audit of current practice
Fever is a common complaint in HIV-1 infected adults and may be a presenting sign of acute HIV-1 infection (AHI). We investigated the extent to which HIV-1 infection was considered...
Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: A systematic review and meta-analysis of randomized controlled trials
Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials comparing efavirenz and...
The meaning and perceived value of mind-body practices for people living with HIV: A qualitative synthesis
Mind-body practices (MBPs) are a subset of complementary medicine that represents a selection of self-care activities that may promote the health of people living with HIV (PLWH). No synthesis of...
