Category Archives: General HIV+ population

Reviews on HIV+ people where the population is not specified

Trends in task shifting in HIV treatment in Africa: Effectiveness, challenges and acceptability to the health professions

2015

BACKGROUND: Task shifting has been suggested to meet the demand for initiating and managing more patients on antiretroviral therapy. Although the idea of task shifting is not new, it acquires...

Determinants of HIV outpatient service utilization: A systematic review

2015

Demands on HIV services are increasing as a consequence of the increased life-expectancy of HIV patients in the highly active antiretroviral therapy era. Understanding the factors that influence utilization of...

Heterosexual risk of HIV transmission per sexual act under combined antiretroviral therapy: Systematic review and bayesian modeling

2014

BACKGROUND: Although essential for patient counseling and quality of life of human immunodeficiency virus (HIV)-infected individuals, the risk of HIV transmission during 1 unprotected sex act with an HIV-infected person...

Isoniazid prophylactic therapy for the prevention of tuberculosis in HIV infected adults: A systematic review and meta-analysis of randomized trials

2015

BACKGROUND: Infection with Human Immunodeficiency virus (HIV) is an important risk factor for Tuberculosis (TB). Anti-Retroviral Therapy (ART) has improved the prognosis of HIV and reduced the risk of TB...

Efficacy of protease inhibitor monotherapy vs. triple therapy: Meta-analysis of data from 2303 patients in 13 randomized trials

2016

OBJECTIVES: The aim of this analysis was to review the evidence and update a meta-analysis evaluating the efficacy and safety results from randomized controlled trials of ritonavir-boosted protease inhibitor (PI/r)...

A systematic review of treatment fatigue among HIV-infected patients prescribed antiretroviral therapy

2015

HIV treatment requires lifelong adherence to medication regimens that comprise inconvenient scheduling, adverse side effects, and lifestyle changes. Antiretroviral adherence and treatment fatigue have been inextricably linked. Adherence in HIV-infected...

System factors as correlates of medication adherence in transplant and HIV populations: A systematic review

2011

Purpose: Medication adherence (MA) is influenced not only by characteristics of the individual patient, but also by factors at the healthcare system level, i.e., micro- (e.g. healthcare worker, social support),...

Impact of geographic and transportation-related barriers on HIV outcomes in sub-Saharan Africa: A systematic review

2014

Difficulty obtaining reliable transportation to clinic is frequently cited as a barrier to HIV care in sub-Saharan Africa (SSA). Numerous studies have sought to characterize the impact of geographic and...

Systemic immune activation in HIV and potential therapeutic options

2014

CONTEXT: Advancement in HIV treatment has evolved over the last two decades with the discovery of new drugs and approaches. Studies have demonstrated that HIV-infected individuals have elevated immune activation...

The enabling effect of food assistance in improving adherence and/or treatment completion for antiretroviral therapy and tuberculosis treatment: A literature review

2014

Socioeconomic costs of HIV and TB and the difficulty of maintaining optimal treatment are well documented. Social protection measures such as food assistance may be required to offset some of...

A systematic review of the usefulness of statin therapy in HIV-infected patients

2015

HIV-infected patients have a greater prevalence of dyslipidemia, earlier incidence and progression of atherosclerosis, and a nearly twofold increased risk for myocardial infarction compared with those not infected with HIV....

The impact of social services interventions in developing countries: A review of the evidence of impact on clinical outcomes in people living with HIV

2015

BACKGROUND: Social service interventions have been implemented in many countries to help people living with HIV (PLHIV) and household members cope with economic burden as a result of reduced earning...

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