Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Unstructured treatment interruption of antiretroviral therapy in clinical practice: A systematic review
Objective To characterize the frequency, reasons, risk factors, and consequences of unstructured anti-retroviral treatment interruptions. Method Systematic review. Results Seventy studies were included. The median proportion of patients interrupting treatment...
Limited benefit of antiretroviral resistance testing in treatment-experienced patients: A meta-analysis
OBJECTIVE: To estimate the effectiveness of resistance assessments based on viral sequencing (genotypic antiretroviral resistance testing, GART), phenotypic antiretroviral resistance testing (PART) or virtual PART (vPART) in the management of...
Is chronic HIV infection associated with venous thrombotic disease? A systematic review
Infection with the human immunodeficiency virus (HIV) is still a major health problem world-wide. HIV infection has changed into a chronic infection with the chance of developing long-term complications. Vascular...
Role of recombinant human growth hormone in HIV-associated wasting and cachexia: Pathophysiology and rationale for treatment
Background: Wasting, or cachexia, is a significant, debilitating, and potentially life-threatening complication of HIV infection. It is associated with reduced strength and functional ability, reduced ability to with stand opportunistic...
Short-course therapy with rifampin plus isoniazid, compared with standard therapy with isoniazid, for latent tuberculosis infection: A meta-analysis
Background. A major difficulty associated with the use of standard therapy with isoniazid for latent tuberculosis infection is poor patient adherence to therapy because of the prolonged course required. Shorter...
Investigating heterogeneity in studies of resting energy expenditure in persons with HIV/AIDS: A meta-analysis
Background: There is conflict in the literature about the extent of alterations of resting energy expenditure (REE) in persons with HIV. Objective: The study was conducted to ascertain the mean...
Social support and HIV-related risk behaviors: A systematic review of the global literature
Existing empirical evidence has well documented the role of social support in both physical and psychological well-being among various populations. In the context of HIV prevention, the rapid increase of...
Clinical studies with chemokine receptor-5 (CCR5)-inhibitors
PURPOSE OF REVIEW: To summarise recently published clinical studies of chemokine receptor-5 (CCR5)-blockers, including the small-molecule blocker, maraviroc (MVC) and CCR5-monoclonal antibodies for HIV. MVC may have immunomodulating properties through...
Cost-effectiveness of HIV/AIDS interventions in Africa: A systematic review of the evidence
BACKGROUND: Evidence for cost-effectiveness of interventions for HIV/AIDS in Africa is fragmentary. Cost-effectiveness is, however, highly relevant. African governments face difficult choices in striking the right balance between prevention, treatment,...
Castleman’s disease: Systematic analysis of 416 patients from the literature
BACKGROUND: Castleman’s disease is a rare primary disease of the lymph nodes with limited available clinical information. METHODS: A systematic literature search identified 416 cases amenable to detailed analysis. RESULTS:...
