Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis
BACKGROUND: Depressive disorders are highly prevalent among people living with HIV (PLWH), severely impairing quality of life and antiretroviral therapy (ART) adherence. While ART advances call for reassessing depressive disorders...
The burden of sarcopenia in people living with HIV: a systematic review and meta-analysis across WHO regions
BACKGROUND: Sarcopenia, characterized by progressive loss of skeletal muscle mass and function, represents an underrecognized comorbidity in people living with human immunodeficiency virus, and comprehensive prevalence data across WHO regions...
Informed Consent in Molecular HIV Epidemiology: A Rapid Review of the Literature to Identify Concerns and Recommendations
In the United States, molecular HIV epidemiology (MHE) is a key part of the National HIV/AIDS Strategy, which incorporates the evaluation of HIV genetic sequences for cluster detection and response....
Prevalence of HIV-associated nephropathy in children: a systematic review with meta-analysis of studies published between 2004 and 2019
INTRODUCTION: Despite major advances in antiretroviral therapy, HIV infection remains a significant global public health challenge. HIV can directly affect the kidneys, leading to HIV-associated nephropathy in children, a condition...
HIV Mortality Surveillance in Nigeria, A Systematic Review of Trends, Determinants, and Implications For Public Health Policy
Despite substantial progress in expanding antiretroviral therapy (ART) coverage and scaling up prevention interventions, Human Immunodeficiency Virus (HIV) related mortality remains a significant public health challenge in several high-burden settings,...
Virus-directed CAR immunotherapies for chronic HBV and HIV: a systematic synthesis of preclinical and early clinical evidences
BACKGROUND: Chronic hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections are among the most important global health issues. Virus-directed CAR-T and CAR-NK are promising strategies capable of targeting...
Commonality and co-occurrence of discrete strategies within implementation strategy bundles: findings from the Living Database of HIV Implementation Science systematic review, 2014-2021
BACKGROUND: HIV services and innovations are delivered through implementation strategy bundles that are often complex, comprising numerous discrete strategies. Systematically characterizing the use patterns of discrete strategies may inform strategy...
Virological outcomes of dolutegravir-based versus other antiretroviral regimens in people living with HIV: A systematic review and meta-analysis
BACKGROUND: Dolutegravir (DTG) is endorsed as a preferred option for both first- and second-line antiretroviral therapy (ART); however, comprehensive high-quality evidence regarding its virological effectiveness is still limited. This review...
The Prevalence and Influencing Factors of Frailty Among Middle-Aged and Older Adults With HIV/AIDS From a Global Perspective: A Systematic Review and Meta-Analysis
AIM: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve...
Peer network approaches for improving HIV testing, prevention and care utilisation among men in sub-Saharan Africa: A scoping review
INTRODUCTION: Limited male engagement in HIV prevention and care is a global challenge more pronounced in sub-Saharan Africa (SSA) contributing to ongoing transmission. However, peer network interventions show promise in...
The risk of infection-related malignancies and tumor mutational burden in immunocompromised hosts: a systematic review and meta-analysis
BACKGROUND: Immunocompromised individuals exhibit an increased risk of malignancies attributable to impaired immune surveillance and increased susceptibility to oncogenic infections, resulting in distinct responses to immunotherapy. The intricacies of infection-related...
Risk factors and mortality rates for children co-infected with HIV and TB in Ethiopia: a systematic review and meta-analysis
This systematic review and meta-analysis aimed to identify risk factors and mortality rates in HIV and TB co-infected children in Ethiopia. An electronic literature search was conducted using multiple databases,...
