Category Archives: General HIV+ population

Reviews on HIV+ people where the population is not specified

Global prevalence of HIV and Mycobacterium tuberculosis co-infection: A systematic review and meta-analysis of 371 included articles

2025

OBJECTIVES: Tuberculosis and Human Immunodeficiency Virus (HIV) are two diseases that have imposed the heaviest burden globally. This study aims to determine the global prevalence of Mycobacterium tuberculosis and HIV...

Determinants of metabolic syndrome in people living with human immunodeficiency virus in Africa: A systematic review and meta-analysis

2025

Background Metabolic syndrome (MetS) among people living with HIV (PLHIV) is an emerging concern in Africa, but its underlying causes remain unclear. This study is a systematic review and meta-analysis...

Factors influencing antiretroviral therapy adherence among youth living with HIV: A systematic review and meta-analysis

2025

Background Adherence to antiretroviral therapy (ART) is vital for controlling the viral load and disease progression in people living with HIV. Previous reviews on ART adherence among youths living with...

Lessons from the field: A systematic review of global and continental prevalence and challenges of people living with HIV (COVID-19)

2025

COVID-19, caused by SARS-CoV-2, accounts for 186 million infections and more than 4 million deaths globally. This systematic review concentrates on the epidemiological profiling of HIV/AIDS, along with the unique...

The prevalence of low-level viraemia and its association with virological failure in people living with HIV: A systematic review and meta-analysis

2024

Low-level viraemia (LLV) following antiretroviral therapy (ART) in people living with HIV (PLWH) has not received sufficient attention. To the determine the prevalence of LLV and its association with virological...

Viral infections and risk of cardiovascular disease: Systematic review and meta-analysis

2025

BACKGROUND: We conducted a systematic review and meta-analysis of studies examining the association of viral infections with the risk of cardiovascular disease, including coronary heart disease (CHD) and stroke. METHODS:...

Global human immunodeficiency virus prevalence and risk behaviors in transmasculine Individuals: A scoping review

2025

PURPOSE: This scoping review sought to synthesize human immunodeficiency virus (HIV) and sexually transmitted infection (STI) prevalence, incidence, risk behaviors, and risk perceptions among transmasculine (TM) individuals globally. METHODS: Eligible...

Deep sequencing reveals underestimated burden of integrase inhibitor resistance mutations in people living with HIV: A global individual patient data meta-analysis

2025

Integrase strand transfer inhibitors (INSTIs) have emerged as cornerstone agents in global antiretroviral therapy, though growing drug resistance presents clinical challenges. Conventional Sanger sequencing may underestimate the burden of low-frequency...

Effect of human immunodeficiency virus on lung function and structure: A systematic review and meta-analysis

2025

Rationale: Obstructive lung disease (OLD) pathogenesis includes inhalational (e.g., smoking) and noninhalational mechanisms (e.g., infections). Human immunodeficiency virus (HIV) has been suggested as a novel OLD risk factor. Substantial data...

Wealth, income and HIV in sub-Saharan Africa: A systematic review

2025

INTRODUCTION: While economic vulnerability is an established driver of health disparities, the relationships between HIV and wealth, income, and economic inequality have been less consistently established. We conducted a systematic...

Effect of same-day HIV treatment initiation (SDI) on 1-year outcomes in low- and middle-income countries: Systematic review and meta-analysis of randomised trials

2025

Introduction Same-day initiation (SDI) of antiretroviral therapy is recommended for people presenting with HIV who have no contraindications. We reviewed the evidence on SDI interventions in low- and middle-income countries...

Efficacy of raltegravir in achieving virological suppression at delivery in HIV-positive pregnant women: A systematic review and meta-analysis

2025

Background The world’s first HIV integrase inhibitor, raltegravir (RAL), has been widely used for the treatment of HIV infection over the past 15 years, and continues benefiting people living with...

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