Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
A narrative review of novel agents for managing heavily treatment-experienced people living with HIV
Objective: The objective of this review is to compare ibalizumab, fostemsavir, and lenacapavir, present the clinical trials evaluating each agent, and provide guidance on their use in highly-treatment experienced (HTE)...
A critical review of mpox outbreaks, risk factors, and prevention efforts in Africa: Lessons learned and evolving practices
OBJECTIVES: In recent years, mpox, a zoonotic disease caused by the mpox virus, has transcended its primary association with Central and West Africa, emerging as a global public health concern....
Barriers and facilitators of physical activity in people living with HIV: A systematic review of qualitative studies
BACKGROUND: Most people living with HIV (PLWH) are sedentary. This study aimed to synthesize the findings of qualitative studies to understand barriers and facilitators of physical activity (PA) among PLWH,...
The impact of analytical treatment interruptions and trial interventions on time to viral re-suppression in people living with HIV restarting ART in cure-related clinical studies: A systematic review and meta-analysis
INTRODUCTION: To assess the effectiveness of novel HIV curative strategies, “cure” trials require periods of closely monitored antiretroviral therapy (ART) analytical treatment interruptions (ATIs). We performed a systematic review and...
Disease intervention specialist-delivered interventions and other partner services for HIV and sexually transmitted infections: A systematic review
INTRODUCTION: Disease intervention specialists (DIS) are critical for delivering partner services programs that provide partner notification, counseling, referral, and other services for HIV, sexually transmitted infections (STIs), and other infections....
Evidence gaps in economic evaluations of HIV interventions targeting young people: A systematic review
Purpose: Young people living with HIV (YPLWH) face the burden of navigating the unique physical, psychological, and social challenges of adolescence while coping with a stigmatized infectious disease that requires lifelong...
A conceptualization and psychometric evaluation of positive psychological outcome measures used in adolescents and young adults living with HIV: A mixed scoping and systematic review
INTRODUCTION: Sub-Saharan Africa bears the greatest burden of HIV, with comorbid mental conditions highly prevalent in people living with HIV. It is important to evaluate the mental health of adolescents...
From conceptualising to modelling structural determinants and interventions in HIV transmission dynamics models: A scoping review and methodological framework for evidence-based analyses
Background Including structural determinants (e.g. criminalisation, stigma, inequitable gender norms) in dynamic HIV transmission models is important to help quantify their population-level impacts and guide implementation of effective interventions that...
Revisiting the prevalence of unhealthy alcohol use among ethnic minority immigrant gay, bisexual men, and other men who have sex with men in North America: A systematic review and meta-analysis
Unhealthy alcohol use is a significant public health concern among ethnic minority immigrant gay, bisexual men, and other men who have sex with men (GBMSM) in North America. The definition...
A scoping review of factors associated with HIV acquisition in the context of humanitarian crises
Humanitarian crises-natural or human-made events that can threaten communities’ health, safety, security, and well-being-may affect the HIV epidemic dynamics. Common aspects of humanitarian crises such as poverty, powerlessness, disruptions to...
Virtual care pathways for people living with HIV: A mixed-methods systematic review
BACKGROUND: The COVID-19 pandemic prompted an unprecedented surge in virtual services, necessitating a rapid shift to digital healthcare approaches. This review focuses on evaluating the evidence of virtual care (VC)...
Managing low-level HIV viraemia in antiretroviral therapy: a systematic review and meta-analysis
OBJECTIVE: HIV-1 management has advanced significantly with antiretroviral therapy (ART), yet challenges persist, including low-level HIV-1 viraemia (LLV). LLV presents a complex scenario, with varied definitions in the literature, reflecting...
