Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
The role of subtyping methodologies in HIV surveillance and vaccine development: A systematic review and meta-analysis
BACKGROUND: HIV genetic diversity has increased over time, with recombinant forms becoming more prevalent and complicating subtype classification and surveillance, particularly in low-and-middle income countries (LMICs). Accurate subtyping is critical...
Colorectal cancer screening uptake and lesion detection in people living with HIV: A systematic review and meta-analysis
Introduction: As people living with HIV age, the absolute colorectal cancer (CRC) burden rises, yet the extent of routine CRC screening delivery and clinical yield is unclear. We synthesized evidence on...
Mapping psychosocial interventions for mental health and well-being among pregnant women living with HIV: A scoping review
BACKGROUND: Pregnant women living with HIV are at increased risk of depression, anxiety, stigma, gender-based violence, and poor engagement in prevention of mother-to-child transmission services. Psychosocial interventions are increasingly used...
Housing instability as a barrier to HIV viral suppression: Evidence from a U.S. systematic review and meta-analysis
Housing instability and homelessness remain pervasive structural determinants of poor HIV outcomes in the United States. People living with HIV (PLWH) who experience homelessness face intersecting barriers, including stigma, behavioral...
Family-centred care for children and adolescents living with HIV in sub-Saharan Africa: A scoping review
Introduction Children and adolescents living with HIV in sub-Saharan Africa (SSA) continue to face significant barriers to diagnosis, treatment adherence, retention in care and psychosocial support, despite progress in prevention...
Global prevalence and biopsychosocial correlates of psychological distress among people living with HIV: An updated theory-informed meta-analysis
Introduction: Psychological distress (PD) is common among people living with HIV (PLWH), but prevalence estimates vary substantially. This study aimed to synthesize the prevalence of PD among PLWH and examine...
Barriers and facilitators to preventing mother-to-child transmission of HIV in sub-Saharan Africa: A scoping review
Women account for 59% of human immunodeficiency virus (HIV) infection cases in sub-Saharan Africa. This impacts the increase in mother-to-child HIV transmission rates and presents challenges to preventive care for...
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis
Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...
A systematic review of obstetric mistreatment among women living with HIV
Several studies have established that women living with HIV frequently encounter mistreatment when accessing maternal healthcare. Previous reviews on obstetric mistreatment have largely focused on the general population, leaving an...
