Category Archives: General HIV+ population

Reviews on HIV+ people where the population is not specified

Detectability of pathogenic RNA virus families in different body sites: A scoping review

2026

Nucleic acid amplification tests (NAATs) are central to modern virology diagnostics. However, evidence supporting alternative specimen types remains uneven across viral families, especially for emerging viruses. This limits diagnostic flexibility...

Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review

2026

Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...

Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies

2026

Background Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...

Broadly neutralizing antibodies for HIV therapy in clinical trials: A systematic review

2026

Background: Lifelong daily antiretroviral therapy (ART) effectively suppresses human immunodeficiency virus type 1 (HIV-1) replication but does not eradicate the virus, underscoring the urgent need for long-acting antivirals and functional cure...

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

2026

Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...

Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis

2026

BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...

Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis

2026

Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...

The impact of HIV coinfection on Mpox patients: A systematic review and meta-analysis

2026

A substantial proportion of mpox cases occur in people with HIV, but how HIV coinfection and immune status affect clinical outcomes remains unclear. We systematically searched major databases up to...

A systematic review of obstetric mistreatment among women living with HIV

2026

Several studies have established that women living with HIV frequently encounter mistreatment when accessing maternal healthcare. Previous reviews on obstetric mistreatment have largely focused on the general population, leaving an...

Retention in care among women with HIV: A systematic review of treatment continuity during pregnancy and postpartum

2026

Introduction Pregnant women with HIV are at risk of reduced engagement in HIV care during pregnancy and postpartum. Retention in care, defined as continuous engagement in HIV-related treatment and follow-up,...

Characterisation of HIV-1 gag cytotoxic T-lymphocyte epitopes in the southern African region—A systematic review

2026

During early HIV‐1 infection, robust Cytotoxic T‐lymphocyte (CTL) responses are mostly targeted at immunodominant Gag p24 epitopes to reduce HIV‐1 viraemia to a set‐point. The aim of this study was...

Prevalence of cardiometabolic diseases among ART-naïve people with HIV: A global systematic review and meta-analysis

2026

Introduction The burden of cardiometabolic diseases (CMDs) is rising in people with HIV (PWH). While extensive data exist on CMD prevalence in PWH receiving antiretroviral therapy (ART), comprehensive data on...

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