Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...
Burden of malaria-HIV coinfection and associated adverse outcomes in Ethiopia: A systematic review and meta-analysis
Background The co-occurrence of malaria and HIV represents a significant health crisis in sub-Saharan Africa, particularly in Ethiopia, where both diseases are prevalent. This synergistic burden aggravates health inequalities, strains...
The prevalence of anxiety disorders among people living with HIV in India: A systematic review and meta-analysis
BACKGROUND: Globally, 301 million face anxiety disorders, notably common among people living with human immunodeficiency virus (PLHIV), causing major challenges and reduced quality of life. AIM: This review assesses India’s...
Incidence and predictors of mortality among adults on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
BACKGROUND: Despite the United Nations’ plan to end Human Immunodeficiency Virus (HIV) as a public health concern by 2030, it remains a significant issue in low-income countries, including Ethiopia. Currently,...
Detectability of pathogenic RNA virus families in different body sites: A scoping review
Nucleic acid amplification tests (NAATs) are central to modern virology diagnostics. However, evidence supporting alternative specimen types remains uneven across viral families, especially for emerging viruses. This limits diagnostic flexibility...
Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review
Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...
Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies
Background Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...
Broadly neutralizing antibodies for HIV therapy in clinical trials: A systematic review
Background: Lifelong daily antiretroviral therapy (ART) effectively suppresses human immunodeficiency virus type 1 (HIV-1) replication but does not eradicate the virus, underscoring the urgent need for long-acting antivirals and functional cure...
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis
Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...
