Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
A review of internet-based testing services for HIV and sexually transmitted infections (STIs)
Key take-home messages The integration of digital technologies into HIV and STI testing is becoming more prevalent, and appears to influence testing behaviours. Three models offering online HIV/STI testing that...
Risk of immune reconstitution inflammatory syndrome with integrase inhibitors versus other classes of antiretrovirals: A systematic review and meta-analysis of randomised trials
Background: Integrase strand transfer inhibitors (InSTIs) decrease HIV plasma viral load faster than other antiretroviral classes. More rapid viral load decline has been associated with higher risk of immune reconstitution inflammatory...
Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa
BACKGROUND: The late recognition of virologic failure (VF) places persons with HIV in Sub-Saharan Africa at risk for HIV transmission, disease progression, and death. We conducted a systematic review and...
Treatment failure and its associated factors among children receiving highly active antiretroviral therapy in Ethiopia: A systematic review and meta-analysis
OBJECTIVES: Over the last decades, large number of children living with human immunodeficiency virus (HIV) have been successfully enrolled in care and initiated treatment. However, treatment failure is still a...
Meta-synthesis and science mapping analysis of HIV/HPV co-infection: A global perspective with emphasis on Africa
BACKGROUND: Viral infections are emerging with diverse clinical relevance both in endemic environments and non-endemic regions of the world. Some of the viruses cause co-infections that are of public health...
The impact of tuberculosis co-infection on virological failure among adults living with HIV in Ethiopia: A systematic review and meta-analysis
Introduction: Tuberculosis (TB) is the most common serious opportunistic infection among people with Human Immunodeficiency Virus (HIV) infection and are considered as the double burden diseases of the world. TB is...
Mixed methods systematic review and metasummary about barriers and facilitators for the implementation of cotrimoxazole and isoniazid—Preventive therapies for people living with HIV
BACKGROUND: Cotrimoxazole and isoniazid preventive therapy (CPT, IPT) have been shown to be efficacious therapies for the prevention of opportunistic infections and tuberculosis (TB) among people living with human immunodeficiency...
Prevalence of frailty and prefrailty in people with human immunodeficiency virus aged 50 or older: A systematic review and meta-analysis
Background: With effective antiretroviral therapy, there is an emerging population of adults aged 50 years or older with human immunodeficiency virus (HIV). Frailty is an increasingly recognized clinical state of vulnerability...
Stressing the need for validated measures of cortisol in HIV research: A scoping review
Objectives: People living with HIV experience numerous endocrine abnormalities and psychosocial stressors. However, interactions between HIV, cortisol levels, and health outcomes have not been well described among people living with HIV...
Global and regional prevalence and outcomes of COVID-19 in people living with HIV: A systematic review and meta-analysis
BACKGROUND: The relationship between HIV (human immunodeficiency virus) and COVID-19 clinical outcome is uncertain, with conflicting data and hypotheses. We aimed to assess the prevalence of people living with HIV...
