Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Association between baseline HIV-1 DNA levels and clinical outcomes in people living with HIV: A meta-analysis of cohort studies
This systematic review and meta-analysis evaluated the effect of digital communication tools (e.g., text message reminders) on improving daily oral HIV pre-exposure prophylaxis (PrEP) adherence. Searching PubMed, Embase, Web of...
Effects of nutritional interventions on nutritional and immunological status and adherence to antiretroviral treatment among adults living with HIV in low- and middle-income countries: Systematic review and meta-analysis
Background HIV/AIDS may cause malnutrition, both directly and indirectly, through common infections. This systematic review and meta-analysis aim to evaluate the effects of nutritional interventions on nutritional status, immunological status,...
Utilization of cervical cancer screening and its associated factors among women living with HIV in East Africa: a systematic review and meta-analysis
Background Women living with HIV (WLHIV), mostly in East Africa, are six times more likely to develop cervical cancer and are a priority population for secondary prevention. Numerous primary studies...
Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of “Universal Test and Treat”: A systematic review and meta-analysis
INTRODUCTION: The “Universal Test and Treat” (UTT) era for antiretroviral therapy (ART) increased HIV service delivery to children and adolescents aged 0-19 with HIV. The goal is to reach %95%...
Free antiretrovirals as a key tool against the HIV pandemic: A systematic review
BACKGROUND/OBJECTIVES: Access to antiretroviral (ARV) drugs remains a critical challenge in achieving the WHO/UNAIDS 95-95-95 targets, with medication costs representing a substantial barrier. This systematic review evaluates the effect of...
Cabotegravir plus rilpivirine injection for virally suppressed persons with HIV-1 infection: A systematic review and meta-analysis of randomized controlled trials
Purpose: This study evaluated the efficacy and safety of cabotegravir/rilpivirine long-acting formulation compared to oral standard of care at 48 and 52 weeks. Method: We conducted an electronic search (2005-2024) across databases...
Evaluating the safety and efficacy of malaria preventive measures in pregnant women with a focus on HIV status: A systematic review and network meta-analysis
Background and Objectives: Malaria poses significant threats to pregnant women, particularly in endemic regions. Preventive measures against it include insecticide-treated bed nets, intermittent preventive treatment, and various supplements. We aimed...
Pharmacokinetic adaptations in pregnancy: Implications for optimizing antiretroviral therapy in HIV-positive women
Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining...
Cannabis use and HIV among Black sexually minoritized men: A systematic review and narrative analysis
Objective: We conducted a systematic review evaluating the extant literature examining the impacts of cannabis use on HIV-related outcomes among Black sexual minoritized men (BSMM). Design: A systematic review. Methods: We conducted a...
Prevalence of suicidal ideation, suicide attempts and suicide deaths in people living with HIV: Are there differences between geographic locations or sexes? : An overview of systematic reviews with meta-analysis
BACKGROUND: Preventing suicide is an important clinical and research priority according to the World Health Organization across lifespan. OBJECTIVE: This study summarizes the prevalence of suicidal ideation, attempts, and suicide...
Comparative safety of B/F/TAF versus other antiretroviral therapy regimens for treatment-naïve people with HIV-1: A systematic literature review and network meta-analysis
Aim: Bictegravir, emtricitabine and tenofovir alafenamide (B/F/TAF) is a single-tablet regimen approved for the treatment of HIV-1 in treatment-naive (TN) and virologically suppressed people with HIV-1 (PWH). While the efficacy of...
