Category Archives: General HIV+ population
Reviews on HIV+ people where the population is not specified
Cause of death and risk of death for people living with HIV admitted to hospital: A systematic review and meta-analysis
Introduction Despite increasing access to HIV treatment and care, HIV-associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living...
Prevalence of different genotypes of HIV-1 in injection drug users in China: A systematic review and meta-analysis
Background: Since 1981, an increasing trend in HIV has been observed for transmission via injection drug users (IDUs), sexual transmission and mother-to-child transmission. The IDUs are blamed for early increases...
Efficacy and safety of doravirine/islatravir for HIV-1: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials
Background: The combination of doravirine and islatravir (DOR/ISL) is a novel two-drug regimen for HIV-1. Early development faced challenges due to dose-dependent immunological signals. We aimed to synthesize the evidence on...
Guidance on the clinical management of HIV-1 persistent low-level viraemia on antiretroviral treatment: A scoping review and an international Delphi consensus
Despite the success of antiretroviral therapy, a subset of people with HIV experience low-level viraemia (LLV), a challenging condition with inconsistent definitions and management across settings. We conducted a scoping...
Relationship quality among people living with HIV/AIDS: A systematic review and meta-analysis
Background The aim of this systematic review and meta-analysis was to summarize the existing literature on the factors associated with relationship quality among people living with HIV (PLWH). Method A...
Empowering women living with HIV through partner-based interventions: A scoping review
Spouses and partners play a crucial role in the well-being of women living with HIV (WLWH), especially in family-oriented cultures. This scoping review examined partner-inclusive interventions to strengthen support systems...
Unmet need for family planning among reproductive-age women living with HIV in Africa: A systematic review and meta-analysis
Background Unmet need for family planning remains a major challenge worldwide, particularly in Africa, contributing to unintended pregnancies, unsafe abortions, and increased maternal morbidity and mortality. Reducing the unmet need...
Syndemics and clinical impact of HIV and mental health conditions among people living with HIV: A systematic review and meta-analysis
INTRODUCTION: People living with HIV (PLWH) may be exposed to harmful political, social, economic and environmental factors that exacerbate their risk of mental health conditions. Such factors can interact synergistically...
Effectiveness of empiric tuberculosis treatment for presumptive smear-negative pulmonary TB among people living with HIV, a systematic narrative review
Introduction: Timely diagnosis and prompt initiation of treatment are crucial for the effective management of tuberculosis (TB), particularly in People living with HIV (PLHIV). A delay in diagnosing TB,in this special...
Experiences and outcomes of peer navigation and support interventions for adolescents on HIV treatment in sub-Saharan Africa: A qualitative evidence synthesis
Adolescents living with HIV (ALHIV) face ongoing challenges with treatment adherence and engagement in care, resulting in lower viral suppression rates compared to adults. Peer navigation has shown promise in...
Telomere length dynamics in adults living with HIV: A systematic review
Background: HIV infection is associated with accelerated biological ageing, with telomere shortening serving as a key biomarker. Although numerous studies have investigated telomere dynamics in people living with HIV (PLWH),...
A synthesis of dimensions of wellbeing among adolescents and young people living with HIV from sub-Saharan Africa for measurement in economic evaluation: A qualitative overview of reviews
Background Adolescents and young people living with HIV (AYPLHIV) in sub-Saharan Africa (SSA) face intersecting structural and psychosocial challenges that compromise their wellbeing, yet these realities are poorly captured by...
