Category Archives: Heterosexual men
The effectiveness of demand creation interventions for voluntary male medical circumcision for HIV prevention in sub-Saharan Africa: A mixed methods systematic review
INTRODUCTION: UNAIDS has recommended that in 14 countries across sub-Saharan Africa (SSA), 90% of men aged 10 to 29 years should be circumcised by 2021 to help reduce transmission of...
Cost-effectiveness of HIV prevention interventions in sub-Saharan Africa: A systematic review
Background: Sub-Saharan Africa carries the highest HIV burden globally. It is important to understand how interventions cost-effectively fit within guidelines and implementation plans, especially in low- and middle-income settings. We reviewed...
Uptake of couples HIV testing and counselling among heterosexual couples in Sub-Saharan Africa: A systematic review and meta-analysis
There is a need for further research to inform policy and practice on Couples HIV Testing and Counselling (CHTC) in Sub-Saharan Africa (SSA). The aim of this systematic review and...
Prevalence and factors associated with fertility desires/intentions among individuals in HIV-serodiscordant relationships: A systematic review of empirical studies
INTRODUCTION: Better knowledge about fertility desires/intentions among HIV-serodiscordant partners who face unique challenges when considering childbearing may be helpful in the development of targeted reproductive interventions. The aim of this...
Preventing sexually transmitted and blood borne infections (STBBIs) among sex workers: A critical review of the evidence on determinants and interventions in high-income countries
BACKGROUND: Across diverse regions globally, sex workers continue to face a disproportionate burden of HIV and other sexually transmitted and blood borne infections (STBBIs). Evidence suggests that behavioural and biomedical...
A systematic review with epidemiological update of male genital schistosomiasis (MGS): A call for integrated case management across the health system in sub-Saharan Africa
Male genital schistosomiasis (MGS) is a gender specific manifestation of urogenital schistosomiasis (UGS) first described in 1911 by Madden in Egypt. Today, while affecting millions of men and boys worldwide,...
Accuracy of anal cytology for diagnostic of precursor lesions of anal cancer: Systematic review and meta-analysis
BACKGROUND: Anal canal carcinoma is relevant because it commonly occurs in high-risk groups, and its incidence has been increasing. OBJECTIVE: This study evaluated the accuracy of anal cytology in the...
A systematic review of adherence to oral pre-exposure prophylaxis for HIV — How can we improve uptake and adherence?
INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent...
Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States
BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...
Economic evaluations of pre- and post-exposure prophylaxis for HIV
Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...
Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis
Quantifying HIV-1 transmission risk per-act of anal intercourse (AI) is important for HIV-1 prevention. We updated previous reviews by searching Medline and Embase to 02/2018. We derived pooled estimates of...
