Category Archives: Heterosexual men
Effectiveness and safety of oral HIV preexposure prophylaxis for all populations
OBJECTIVE: Preexposure prophylaxis (PrEP) offers a promising new approach to HIV prevention. This systematic review and meta-analysis evaluated the evidence for use of oral PrEP containing tenofovir disoproxil fumarate as...
Male partners’ involvement in prevention of mother-to-child HIV transmission in sub-Saharan Africa: A systematic review
In sub-Saharan Africa (SSA), male partners are rarely present during prevention of mother-to-child transmission (PMTCT) services. This systematic review aims to synthesize, from a male perspective, male partners’ perceived roles,...
HIV pre-exposure prophylaxis (PrEP): A review of current knowledge of oral systemic HIV PrEP in humans
PURPOSE: Despite established HIV prevention strategies and broadly available diagnostic strategies in developed western countries, rates of HIV new infections remain high. Alternative strategies for HIV prevention, particularly among men...
Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis
OBJECTIVES: Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual populations in both high-income and...
Systematic review of strategies to increase men’s HIV-testing in sub-Saharan Africa
OBJECTIVE: This systematic review summarizes evidence on the effectiveness of strategies to increase men’s HIV-testing in sub-Saharan Africa. METHODS: Medline, EmBase, Africa-Wide Information and Global Health were searched. Cluster and...
The cost and impact of scaling up pre-exposure prophylaxis for HIV prevention: A systematic review of cost-effectiveness modelling studies
BACKGROUND: Cost-effectiveness studies inform resource allocation, strategy, and policy development. However, due to their complexity, dependence on assumptions made, and inherent uncertainty, synthesising, and generalising the results can be difficult....
Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States
A meta-analysis was performed to examine the effects of 14 behavioral and social interventions for heterosexual adults on their adoption of safer sex behaviors or incidence of sexually transmitted diseases...
Behavioural interventions for HIV positive prevention in developing countries: A systematic review and meta-analysis
Objective To assess the evidence for a differential effect of positive prevention interventions among individuals infected and not infected with human immunodeficiency virus (HIV) in developing countries, and to assess...
Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: A meta-analysis
This meta-analysis investigated human papillomavirus (HPV) prevalence in vulvar, vaginal and anal intraepithelial neoplasia (VIN, VAIN, AIN) grades 1-3 and carcinoma from 93 studies conducted in 4 continents and using...
Heterosexual risk of HIV infection in China: Systematic review and meta-analysis
BACKGROUND: Heterosexual sex has become the dominant transmission route in China. Recently studies reported high heterogeneity in heterosexual transmission risk in resource-limited countries. The aim of this study was to...
Do prevention interventions reduce HIV risk behaviours among people living with HIV? A meta-analytic review of controlled trials
Objective: To conduct a meta-analytic review of HIV interventions for people living with HIV (PLWH) to determine their overall efficacy in reducing HIV risk behaviours and identify intervention characteristics associated...
