Category Archives: Older adults (>50 years)

Aging with HIV

2019

PURPOSE OF REVIEW: This review points out unmet medical needs and open research questions of older adults living with HIV. Starting from the definition of aging in HIV, it explores...

Antiretroviral therapy improves neurocognitive impairment in people living with HIV? A meta-analysis

2020

Objectives: Although effective antiretroviral therapy (ART) has been used for more than two decades, HIV-associated neurocognitive disorder remains prevalent. Thus, whether ART can improve neurocognitive impairment is controversial. This review...

Barriers to older adults seeking sexual health advice and treatment: A scoping review

2020

BACKGROUND: Sexual health is an integral part of overall health in older age. Research consistently reports that heterosexual and queer older people tend not to disclose sexual concerns and difficulties...

Direct-acting antivirals for HCV treatment in older patients: A systematic review and meta-analysis

2020

The advent of highly effective and well-tolerated direct antiviral antivirals (DAAs) has dramatically changed the landscape of chronic hepatitis C. The effect of DAAs in older adults is difficult to...

HIV care among elderly population: Systematic review and meta-analysis

2020

Elderly people living with HIV are increasing. At present in the United States, nearly half of newly diagnosed HIV-infected people are aged >50 years. Diagnosis and treatment of HIV-infected elderly...

Immunological and virological responses in older HIV-infected adults receiving antiretroviral therapy: An evidence-based meta-analysis

2020

Millions of people living with the human immunodeficiency virus (HIV) have received antiretroviral therapy (ART). Older adults make up a significant portion of these individuals, however, the immunological and virological...

Factors associated with general sexual functioning and sexual satisfaction among people living with HIV: A systematic review

2019

Sexual difficulties, experienced by half of the people living with HIV (PLWH), not only affect quality of life but have been associated with lower adherence to antiretroviral medication. This systematic...

Out-of-pocket costs associated with HIV in publicly funded high-income health care settings

2019

Key take-home messages The aging of the people living with HIV in care is leading to increased HIV care costs. There is considerable inter-jurisdictional heterogeneity in the cost-sharing policies for...

Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus

2019

BACKGROUND: Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its...

Physical activity and HIV in sub-Saharan Africa: A systematic review of correlates and levels

2018

Background: Self-management strategies such as physical activity (PA) can address disability and optimize mental, physical, social and economic outcomes for persons living with HIV (PLWH). Understanding factors that influence PA...

Meta-analysis of adherence to highly active antiretroviral therapy in patients with HIV infection in China

2018

With the widespread implementation of antiretroviral therapy in many countries, the HIV/AIDS epidemic has declined. However, little is known about the prevalence of adherence rate to Highly Active Antiretroviral Therapy...

Older African Americans and the HIV care continuum: A systematic review of the literature, 2003-2018

2018

Evidence suggests that racial disparities in the HIV care continuum persist in older age groups, particularly among African Americans. The objective of this systematic review was to identify factors that...

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