Category Archives: Older adults (>50 years)
Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: A challenge to success
Objective: There is considerable research around the morbidity and mortality related to noncommunicable diseases (NCDs), particularly cardiovascular disease and diabetes, among people living with HIV/AIDS (PLWHA) in resource-richer settings. Less...
A review of premature frailty in HIV-infected persons; another manifestation of HIV-related accelerated aging
PURPOSE: HIV-related immunological and multisystem accelerated aging contributes to the premature occurrence of age-related comorbidities. Such non-AIDS-defining comorbidities include cardiovascular disease, dyslipidemia, osteoporosis and frailty, and are of increasing importance...
More than 20 years of research into the quality of life of people with HIV and AIDS–a descriptive review of study characteristics and methodological approaches of published empirical studies
BACKGROUND: The quality of life of people living with HIV and AIDS (PLWHA) is becoming increasingly important–a fact that is also reflected in extensive research efforts. Owing to the almost...
Prevention of HIV among older adults: A literature review and recommendations for future research
OBJECTIVE: This study reviews the existing literature on the prevention of HIV among older adults, including universal and indicated prevention programs and prevention strategies. METHOD: A literature search was conducted...
Aging, antiretrovirals, and adherence: A meta analysis of adherence among older HIV-infected individuals
INTRODUCTION: Older adults are generally considered to be at greater risk for medication non-adherence due to factors such as medication complexity, side effects, cost, and cognitive decline. However, this generalization...
Household impacts of AIDS: Using a life course approach to identify effective, poverty-reducing interventions for prevention, treatment and care
A life course approach was used to assess household level impacts and inform interventions around HIV risk and AIDS vulnerability across seven major age-related stages of life. Our focus was...
Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: A systematic review and meta-analysis
Antiretroviral-therapy rollout in resource-poor countries is often associated with limited, if any, HIV-RNA monitoring. The effect of variable monitoring on the emergence of resistance after therapy with commonly used drug...