Category Archives: Other

Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)

Linkage-to-care methods and rates in U.S. emergency department-based HIV testing programs: A systematic literature review brief report

2016

BACKGROUND: An increasing number of U.S. emergency departments (EDs) have implemented ED-based HIV testing programs since the Centers for Disease Control and Prevention issued revised HIV testing recommendations for clinical...

Zoonotic and vector-borne infections among urban homeless and marginalized people in the United States and Europe, 1990-2014

2016

INTRODUCTION: In high-income countries, homeless individuals in urban areas often live in crowded conditions with limited sanitation and personal hygiene. The environment of homelessness in high-income countries may result in...

Ritonavir-boosted darunavir plus two nucleoside reverse transcriptase inhibitors versus other regimens for initial antiretroviral therapy for people with HIV infection: A systematic review

2017

BACKGROUND: Darunavir is a second-generation protease-inhibitor used with ritonavir (DRV/r) and two nucleoside reverse-transcriptase inhibitors as an option in first-line antiretroviral treatment (ART). METHODS: We systematically reviewed randomized controlled trials...

Evidence-based review of statin use in patients with HIV on antiretroviral therapy

2017

INTRODUCTION: As a result of improved safe and effective therapeutic options for human immunodeficiency virus (HIV), life expectancy of those living with HIV is increasing leading to new challenges (e.g.,...

Zidovudine/lamivudine vs. abacavir/lamivudine vs. tenofovir/emtricitabine in fixed-dose combinations as initial treatment for HIV patients: A systematic review and network meta-analysis

2017

INTRODUCTION: Initial treatment of the HIV is based on the use of three drugs, two of which are nucleoside analog reverse-transcriptase inhibitors. There are three combinations of these drugs which...

Pharmacogenetic considerations for HIV treatment in different ethnicities: An update

2017

INTRODUCTION: Variations in the human genome sequence sometimes play an important role in pharmacokinetics and/or pharmacodynamics. Previous studies have demonstrated a high degree of variation both between and within different...

Nucleoside reverse transcriptase inhibitor-reducing strategies in HIV treatment: Assessing the evidence

2017

Antiretroviral (ARV) therapy, comprising a backbone of two nucleos(t)ide reverse transcriptase inhibitors (NRTIs) plus another ARV, is the recognized standard of care (SOC), which has helped extend life expectancy in...

Geographic distribution and temporal trends of HIV-1 subtypes through heterosexual transmission in China: A systematic review and meta-analysis

2017

Background: Heterosexual transmission (HST) has become the current predominant transmission pathways of the HIV-1 epidemic in China. The aim of this study was to explore the geographic and dynamic change...

The sexual lives of people with disabilities within low- and middle-income countries: A scoping study of studies published in English

2017

BACKGROUND: Although approximately 80% of the global population of people with disabilities reside in low- and middle-income countries (LMICs), very little is known about their sexual lives due to a...

Barriers to HIV remission research in low- and middle-income countries

2017

INTRODUCTION: HIV eradication and remission research has largely taken place in high-income countries. In low- and middle-income countries (LMIC), there may be factors that have a substantial impact on the...

Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades

2016

BACKGROUND: In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and partners set the ’90-90-90 targets’; aiming to diagnose 90% of all HIV positive people, provide antiretroviral...

The emergence and evolution of the research fronts in HIV/AIDS research

2017

In this paper, we have identified and analyzed the emergence, structure and dynamics of the paradigmatic research fronts that established the fundamentals of the biomedical knowledge on HIV/AIDS. A search...

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