Category Archives: Other

Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)

Treatment of cryptosporidiosis in immunocompromised individuals: Systematic review and meta-analysis

2007

Cryptosporidium is a common cause of gastroenteritis and is associated with severe life-threatening illness among immunocompromised individuals. This review aimed to assess the efficacy of interventions for the treatment and...

The effect on treatment adherence of administering drugs as fixed-dose combinations versus as separate pills: Systematic review and meta-analysis

2014

Administering drugs as fixed-dose combinations (FDCs) versus the same active drugs administered as separate pills is assumed to enhance treatment adherence. We synthesized evidence from randomized controlled trials (RCTs) about...

Gender difference in HIV RNA levels: A meta-analysis of published studies

2002

Plasma HIV RNA copy number is a strong prognostic marker of progression to AIDS in antiretroviral-naive persons. Recent research suggests women have lower HIV RNA levels than comparable men. Because...

Integrated delivery of HIV and tuberculosis services in sub-Saharan Africa: A systematic review

2011

Tuberculosis is a major cause of morbidity and mortality in people with HIV and about a quarter of HIV-related deaths are attributed to tuberculosis. In this Review we identify and...

Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: An updated meta-analysis

2011

The aspartate aminotransferase-to-platelet ratio index (APRI), a tool with limited expense and widespread availability, is a promising noninvasive alternative to liver biopsy for detecting hepatic fibrosis. The objective of this...

Interventions to improve the health of the homeless: A systematic review

2005

BACKGROUND: Homelessness is a widespread problem in the United States. The primary goal of this systematic review is to provide guidance in the development and organization of programs to improve...

HIV transmission risk through anal intercourse: Systematic review, meta-analysis and implications for HIV prevention

2010

BACKGROUND: The human immunodeficiency virus (HIV) infectiousness of anal intercourse (AI) has not been systematically reviewed, despite its role driving HIV epidemics among men who have sex with men (MSM)...

Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort

2011

OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...

Etravirine: a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV

2009

BACKGROUND: Since 1981, the AIDs epidemic has continued to expand and, at the end of 2007, there were ~33 million people worldwide living with HIV, including 1.2 million in North...

Dried fluid spots for HIV type-1 viral load and resistance genotyping: A systematic review

2009

BACKGROUND: Dried spots on filter paper made of whole blood (dried blood spots; DBS), plasma (dried plasma spots; DPS) or serum (dried serum spots) hold promise as an affordable and...

Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS

2013

Background: UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse...

Quality assessment of capture-recapture studies in resource-limited countries

2011

Objectives Resource-limited countries often lack robust routine surveillance systems to accurately assess the burden of human attributes and diseases. In these settings capture-recapture analysis can be an alternative tool to...

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