Category Archives: Other
Reviews that are lab-based (e.g. genes, pharmaceuticals) or on unique groups of people (e.g. fishermen, nurses)
HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...
Rifapentine vs. rifampicin for the treatment of pulmonary tuberculosis: A systematic review
OBJECTIVE: To evaluate the efficacy and safety of rifapentine (RPT) vs. rifampicin (RMP) for the treatment of pulmonary tuberculosis (PTB). DESIGN: Systematic review of randomised controlled trials (RCTs) that compared...
The quest for multi-sectoral HIV/AIDS prevention in Central and Eastern Europe and why it matters
Background: The HIV/AIDS epidemic is continuing to expand in Central and Eastern Europe against a background of transition and disparities in welfare. In absence of a multi-sectoral HIV/AIDS prevention strategy...
Viral infections in workers in hospital and research laboratory settings: A comparative review of infection modes and respective biosafety aspects
Objectives: To compare modes and sources of infection and clinical and biosafety aspects of accidental viral infections in hospital workers and research laboratory staff reported in scientific articles. Methods: PubMed,...
Tipranavir: The first nonpeptidic protease inhibitor for the treatment of protease resistance
Background: Despite the availability of a growing number of potent antiretroviral agents, efforts to completely suppress viral replication in patients with HIV-1 infection are limited because of the increasing risk...
Are females who inject drugs at higher risk for HIV infection than males who inject drugs: An international systematic review of high seroprevalence areas
Objective: There are multiple reasons why females who inject drugs may be more likely to become infected with HIV than males who inject drugs. Where this is the case, special...
Pulmonary resection for patients with multidrug-resistant tuberculosis: Systematic review and meta-analysis
OBJECTIVES: Multidrug-resistant tuberculosis (MDR-TB) has become an emerging global public health crisis. Several studies have suggested that pulmonary resection has efficacy in the treatment of MDR-TB. A systematic review of...
Interferon-gamma release assays for the diagnosis of tuberculosis and tuberculosis infection in HIV-infected adults: A systematic review and meta-analysis
BACKGROUND: Despite the widespread use of interferon-gamma release assays (IGRAs), their role in diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains unclear. We conducted a comprehensive systematic review...
Peginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV co-infection: A systematic review and economic evaluation
OBJECTIVE: to assess the clinical effectiveness and cost-effectiveness of peginterferon alfa and ribavirin for the treatment of chronic hepatitis c virus (HCV) in three specific patient subgroups affected by recent...