Category Archives: Transgender communities

Indirect treatment comparison of the efficacy of long-acting injectable cabotegravir compared with lenacapavir for HIV pre-exposure prophylaxis

2026

INTRODUCTION: Long-acting injectable cabotegravir (hereafter referred to as cabotegravir) is the first long-acting injectable approved for pre-exposure prophylaxis (PrEP) based on the HPTN 083 and 084 trials. Long-acting injectable lenacapavir...

Determinants of Cardiovascular Disease Risk Among LGBTQ+ Populations: A Systematic Review of Empirical Evidence

2026

BACKGROUND: Understanding the multifactorial drivers of cardiovascular disease (CVD) risk in LGBTQ+ populations is critical to advancing equitable cardiovascular care. OBJECTIVE: To evaluate and synthesize empirical evidence on factors influencing...

Assessing the State of Published HIV Research Concerning Sexual Minority Women: A Global English Language Scoping Review

2026

PURPOSE: We conducted a scoping review to map peer-reviewed literature on HIV research concerning sexual minority women (SMW). METHODS: Following guidance from Arksey and O’Malley’s framework and the Preferred Reporting...

Assessment of knowledge and use of HIV primary and secondary prevention strategies in Portugal: a scoping review

2026

BACKGROUND: Portugal has been committed to achieve UNAIDS target goals by the end of 2030 by improving accessibility of prevention programs to the general population and key populations. However, Portugal...

Global mental health disparities among transgender women and transfeminine people living with HIV: A systematic review and meta-analysis of 63 studies

2026

BACKGROUND: Transgender women and transfeminine people face a disproportionate burden of mental health conditions driven by stigma, discrimination, and structural inequities, with additional psychosocial challenges related to HIV diagnosis and...

HIV risk and prevention among cisgender men who have sex with transgender women or transfeminine nonbinary people

2026

Key take-home messages

HIV prevalence in transgender women and cisgender men who have sex with men in sub-Saharan Africa

2025

Introduction: The Global AIDS Strategy 2021–2026 calls for equitable access to HIV services for all populations. Transgender people have been marginalized and experience disproportionate risk of HIV infection in sub-Saharan...

Barriers and facilitators influencing PrEP uptake among men who have sex with men and transgender women in the United States: A systematic review

2026

In the United States, men who have sex with men (MSM) and transgender women (TGW) have high HIV pre-exposure prophylaxis (PrEP) awareness, yet uptake rates remain extremely low. This signifies...

A scoping review of the methods, content, and populations of rural LGBTQ health research since the new millennium

2026

INTRODUCTION: This scoping review mapped the population characteristics, methodologies, content, and publishing trends of primary research focused on rural LGBTQ individuals since the year 2000. METHODS: We conducted a search...

Evaluating the effectiveness of digital health interventions for HIV prevention and treatment adherence among transgender populations: A systematic review and meta-analysis

2026

Background Transgender individuals face a disproportionate burden of HIV due to systemic barriers including stigma, discrimination, and limited access to gender-affirming healthcare. Digital health interventions (DHIs), such as mobile applications,...

Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence

2026

Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...

Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review

2025

INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...

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