Category Archives: Women

Zidovudine use in pregnancy and congenital malformations

2017

OBJECTIVE: There is inconsistent evidence that zidovudine use during pregnancy increases overall, cardiac, and male genital malformations. DESIGN: We conducted a systematic review and meta-analysis of zidovudine use and malformations...

Leveraging the U.S. criminal justice system to access women for HIV interventions

2017

The criminal justice (CJ) system can be leveraged to access women for HIV prevention and treatment programs. Research is lacking on effective implementation strategies tailored to the specific needs of...

Elective cesarean section for women living with HIV: A systematic review of risks and benefits

2017

OBJECTIVE AND DESIGN: To inform WHO guidelines, we conducted a systematic review and meta-analysis to assess maternal and perinatal outcomes comparing cesarean section (c-section) before labor and rupture of membranes...

The experience of pregnancy in women living with HIV: A meta-synthesis of qualitative evidence

2017

The lived experience of pregnancy from the perspectives of women living with HIV (WLWH) is not well understood. We aimed to understand the meaning of pregnancy for WLWH. A meta-synthesis...

HIV risk reduction interventions among substance-abusing reproductive-age women: A systematic review

2017

HIV/AIDS is one of the leading causes of death among reproductive-age women throughout the world, and substance abuse plays a major role in HIV infection. We conducted a systematic review,...

Female and younger subjects have lower adherence in PrEP trials: A meta-analysis with implications for the uptake of PrEP service to prevent HIV

2017

OBJECTIVE: To estimate the medicine-taking compliance (MTC) level, explore its facilitators and barriers, and quantify the association between MTC level and pre-exposure prophylaxis (PrEP) protective efficacy in individuals at risk...

Critical review: Review of the efficacy, safety, and pharmacokinetics of raltegravir in pregnancy

2016

Raltegravir was previously considered an alternative antiretroviral in pregnancy because of limited data, but recent pregnancy guidelines recommend raltegravir as a preferred integrase treatment option. Data from published articles and...

Understanding the experiences of married Southern African women in protecting themselves from HIV/AIDS: A systematic review and meta-synthesis

2017

BACKGROUND: Whilst marriage has been repeatedly identified in the literature as an HIV risk factor amongst Southern African women, not much is known about women’s perception of their role, experiences...

HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment

2016

OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...

Review of HIV treatment progress, gaps, and challenges in the Caribbean, 2005-2015

2016

Objective: To highlight the current context of the HIV response in the Caribbean and what remains to be addressed to close gaps in HIV treatment and care and end AIDS...

The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: A systematic review

2017

BACKGROUND: Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between...

Non-specialist psychosocial support interventions for women living with HIV: A systematic review

2017

Many women living with HIV experience a range of physical, social, and psychological challenges linked to their HIV status. Psychosocial support interventions may help women cope with these challenges and...

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