Category Archives: Prevention, Engagement and Care Cascade
Incidence and predictors of opportunistic infection among people living with HIV in Ethiopia: A systematic review and meta-analysis
Background Opportunistic infections (OIs) play a crucial role in the morbidity and mortality of HIVâinfected individuals. Despite the increasing use of antiretroviral therapy, there remains a lack of comprehensive data...
Mental health of women with HIV: A qualitative meta-synthesis
BACKGROUND: Women living with human immunodeficiency virus (HIV) experience significant psychological burdens due to biological and gendered factors such as pregnancy, childbirth and breastfeeding. However, a life course-based understanding of...
The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: A comprehensive review
Co-infection of HIV and HBV is still a major global public health concern. Co-infected people have a nearly threefold increased risk of end-stage liver disease, with a noticeably faster development...
Preferences for long-acting antiretroviral therapy among people with HIV: A systematic review of discrete choice experiments
BACKGROUND: Long-acting antiretroviral therapy (LA-ART) is emerging as a promising strategy to enhance treatment satisfaction and improve the quality of life for people living with HIV (PLWH). A comprehensive understanding...
Interventions to reduce HIV-related stigma among older people living with HIV in sub-Saharan Africa: A scoping review
HIV-related stigma remains a major barrier to testing, treatment, and quality of life, especially for the growing population of older people living with HIV (OPLWH, aged 50+). Such stigma intersects...
PrEP delivery for US adolescents and young adults: A systematic review and narrative synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review
INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...
Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis
Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....
Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response
Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...
