Category Archives: Prevention, Engagement and Care Cascade
Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
Interventions to increase adherence to antiretroviral therapy in people living with HIV—what works? A systematic review and meta-analysis
The Perceptions and Practicalities Approach (PaPA) is a recommended framework for designing medication adherence interventions. Little is known about the utility of the PaPA framework in improving antiretroviral therapy (ART)...
Prevalence and risk factors for oropharyngeal, esophageal, and oral candidiasis in HIV-positive individuals: A systematic review and meta-analysis
Background: Oral, oropharyngeal, and esophageal candidiasis are common forms of mucosal candidiasis (MC) in people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Despite differences in infection sites, oral, oropharyngeal, and...
Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis
INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...
The global re-emergence of syphilis and antimicrobial resistance among men who have sex with men (MSM), people living with HIV (PLWH), and newborns: A narrative review
Syphilis incidence continues to rise substantially among men who have sex with men (MSM), people living with HIV (PLWH), newborns, and women of reproductive age, despite preventive measures and available...
The mental health of adults living with HIV in sub-Saharan Africa: Interventions along the HIV care continuum—A systematic review
Although the relationship between HIV and mental health is well-established, limited research has focused on the available interventions for adults living with HIV (ALWH), particularly those in sub-Saharan Africa (SSA)...
Can ChatGPT match physicians in the diagnosis, triage, management and prevention of infectious diseases? A scoping review
INTRODUCTION: The global burden of infectious diseases (ID), combined with a shortage of ID specialists, continues to challenge healthcare systems worldwide. Artificial intelligence (AI), particularly large language models such as...
Barriers and facilitators to STI and HIV testing among African and Caribbean heritage communities in high-income countries mapped to the behaviour change wheel: A scoping review
Background: African and Caribbean communities in high-income countries face disproportionate sexually transmitted infection (STI) risks. In the US, the gonorrhoea rate among non-Hispanic Blacks is 7.7 times greater than that among...
Choosing between dual and three-drug antiretroviral therapy in aging and comorbid people with HIV: A narrative review
The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...
Dysregulated metabolism in people living with HIV in the modern ART-era: A systematic review of targeted metabolomics studies
HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy...
Maternal-to-child-transmission of human immunodeficiency virus in maternal preterm premature rupture of the membranes: A systematic review
Aim: Preterm premature rupture of membranes (PPROM) in the context of maternal human immunodeficiency virus (HIV) infection poses a significant clinical dilemma, as clinicians must balance the risks of prematurity with...
Barriers and facilitators to oral HIV pre-exposure prophylaxis use in Australia: A scoping review comparing findings to Canada, New Zealand, and the United Kingdom
Oral HIV pre-exposure prophylaxis (PrEP) is highly effective, yet various barriers limit its potential as a HIV prevention strategy. This scoping review aimed to identify and quantify determinants of oral...
