Category Archives: Engagement and Care Cascade

What is polypharmacy in people living with HIV/AIDS? A systematic review

2022

Polypharmacy in people living with HIV/AIDS (PLWHA) is a rising morbidity that exacts hefty economic burden on health budgets in addition to other adverse clinical outcomes. Despite recent advances, uncertainty...

Impact of the COVID-19 pandemic on HIV healthcare service engagement, treatment adherence, and viral suppression in the United States: A systematic literature review

2022

The COVID-19 pandemic has necessitated adaptations in how healthcare services are rendered. However, it is unclear how these adaptations have impacted HIV healthcare services across the United States. We conducted...

Digital directly observed therapy to monitor adherence to medications: A scoping review

2022

Background: Technology-based directly observed therapy (DOT) is more cost-effective and efficient compared with in-person monitoring visits for medication adherence. While some evidence shows these technologies are feasible and acceptable, there...

Digital sexually transmitted infection and HIV services across prevention and care continuums: Evidence and practical resources

2022

Increased demand for sexual health services (including prevention and treatment) have spurred the development of digital STI/HIV services. Earlier advances in testing technologies opened the door for self-testing and self-sampling...

Leveraging resilience-supportive strategies to enhance protective factors in young sexual minority men: A scoping review of HIV behavioral interventions implemented in high-income countries

2022

Behavioral HIV interventions focused on strengthening young sexual minority men’s (SMM) internal (assets) and external (resources) protective factors are promising, yet their evaluation as resilience-supportive strategies to minimize or negate...

The proportion of loss to follow-up from antiretroviral therapy (ART) and its association with age among adolescents living with HIV in sub-Saharan Africa: A systematic review and meta-analysis

2022

BACKGROUND: Human immunodeficiency virus (HIV) remains a global health threat, especially in developing countries. The successful scale-up of antiretroviral therapy (ART) programs to address this threat is hindered by a...

Implementation science for the prevention and treatment of HIV among adolescents and young adults in sub-Saharan Africa: A scoping review

2022

Despite many evidence-based adolescent and young adult (AYA) HIV interventions, few are implemented at scale in sub-Saharan Africa (SSA). A growing implementation science literature provides important context for scaling up...

Health-related needs reported by adolescents living with HIV and receiving antiretroviral therapy in sub-Saharan Africa: A systematic literature review

2022

INTRODUCTION: Adolescents living with HIV (ALHIV) on antiretroviral therapy (ART) have specific health needs that can be challenging to deliver. Sub-Saharan Africa (SSA) is home to 84% of the global...

Elevated neopterin in tuberculosis and co-infection with HIV and the effect of treatment: A systematic review, meta-analysis, and meta-regression

2022

BACKGROUND: Neopterin (NEO) is a marker of immune stimulation. Increased NEO levels have been associated with autoimmune diseases, infections, and malignancies. Studies of NEO alterations in tuberculosis (TB) with or...

The social, behavioral, and ethical modalities of COVID-19 on HIV care in South Africa: A systematic review

2022

The profound public health impact of the novel outbreak of the SARS-CoV-2 virus in 2019 has been unparalleled in the last century. Rapid spread of the disease and a high...

Factors influencing treatment adherence in hypertension and HIV management in South Africa: A comparative literature review

2022

BACKGROUND: Hypertension (HTN) is the most significant risk factor for cardiovascular disease (CVD) in South Africa (SA), with one in three people over the age of 25 suffering from HTN....

Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

2022

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings...

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