Category Archives: Treatment
Sexual and reproductive health and rights, HIV and migration in southern Africa: A rapid review
Migration, a prevalent global phenomenon, significantly impacts health, particularly in low- to middle-income countries. This article presents a rapid review aimed at mapping projects, lessons and policies concerning sexual and...
Prevalence of mental health problems in people living with HIV: A systematic review and meta-analysis
HIV remains a significant public health concern, with an estimation of 39 million people infected. There is a lack of universally accepted benchmarks for prevalence of mental health problems among...
The long-term health outcomes of people living with perinatal human immunodeficiency virus: A scoping review
Since the first reported cases of perinatally acquired human immunodeficiency virus (HIV) in 1982, a generation born with HIV has reached adulthood. The authors conducted a scoping review of PubMed...
Adverse perinatal outcomes associated with different classes of antiretroviral drugs in pregnant women with HIV
Objective: Women with HIV (WHIV) are at an increased risk of adverse perinatal outcomes compared to women without HIV, despite antiretroviral therapy (ART). There is evidence that the risk of...
Reducing the risk of HIV/AIDS transmission using intervention mapping: A systematic review
Intervention mapping (IM) is a planning approach that reflects the intricate decision-making process involved in the design of behavior interventions. The development and implementation of IM is complex in preventing...
Impact of the COVID-19 pandemic on the HIV care continuum and associated factors in middle-income countries: A mixed-methods systematic review
INTRODUCTION: The HIV care continuum during the COVID-19 era faced specific challenges. The pandemic, affecting the delivery of HIV care, exacerbated existing healthcare inequities and vulnerabilities in middle-income countries with...
Non-pharmaceutical interventions for people living with HIV with cognitive impairment: A scoping review
BACKGROUND: Cognitive impairment (CI) in HIV is often of multifactorial causation, and remains a prominent issue in the age of effective combination antiretroviral therapy (cART), affecting approximately 14% of people...
Effect of micronutrients on HIV-related clinical outcomes among adults living with HIV on antiretroviral therapy: Systematic review and meta-analysis
Context: Micronutrient deficiencies are common and frequently co-occurring among people living with HIV (PLHIV) globally, with consequences for their health and clinical outcomes. Previous reviews of the influence of micronutrient supplementation...
Risk of viral failure after simplification therapy without using integrase inhibitors compared with maintenance of triple antiretroviral therapy: A systematic review and meta-analysis
Background Antiretroviral drug simplification is a strategy to reduce drug exposure and improve treatment adherence. Nowadays, dolutegravir plus lamivudine is the most preferred regimen, which might lead in the future...
Antiviral therapy for cytomegalovirus retinitis: A systematic review and meta-analysis
Cytomegalovirus retinitis (CMVR) is a significant cause of blindness in patients with advanced acquired immunodeficiency syndrome (AIDS). There are no established guidelines for its treatment, resulting in varied antiviral approaches....
The impact of undernutrition and anemia on HIV-related mortality among children on ART in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Although there have been significant advancements in providing HIV-infected children with access to antiretroviral therapy (ART), the mortality rates have remained unacceptably high. Inadequate nutrient intake or absorption is...
