Category Archives: Treatment
Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: A scoping review
Background HIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including U = U (Undetectable = Untransmittable). Effective interventions are crucial to support these...
Colliding wars: A systematic review on HIV responses in conflict-affected settings
BACKGROUND: Armed conflicts are an escalating threat to public health, often marked by violence, poverty, displacement and weakened health systems-conditions that mirror the drivers of HIV transmission. AIM: This review...
Oral manifestations in HIV-positive individuals under highly active antiretroviral therapy: A systematic review and meta-analysis of prevalence data
This study aims to analytically explore the prevalence of oral manifestations in HIV-positive patients who are receiving or are not receiving highly active antiretroviral therapy (HAART). Electronic search was conducted...
Systematic review and network meta-analysis of psychosocial interventions on antiretroviral therapy adherence
BACKGROUND: Antiretroviral therapy (ART) is crucial for prolonging the lives of people with human immunodeficiency virus (HIV), but adherence remains suboptimal. Psychosocial interventions show promise for improving ART adherence, yet...
Incidence and predictors of opportunistic infection among people living with HIV in Ethiopia: A systematic review and meta-analysis
Background Opportunistic infections (OIs) play a crucial role in the morbidity and mortality of HIV‐infected individuals. Despite the increasing use of antiretroviral therapy, there remains a lack of comprehensive data...
Mental health of women with HIV: A qualitative meta-synthesis
BACKGROUND: Women living with human immunodeficiency virus (HIV) experience significant psychological burdens due to biological and gendered factors such as pregnancy, childbirth and breastfeeding. However, a life course-based understanding of...
The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: A comprehensive review
Co-infection of HIV and HBV is still a major global public health concern. Co-infected people have a nearly threefold increased risk of end-stage liver disease, with a noticeably faster development...
Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis
Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....
Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response
Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...
