Category Archives: Treatment
Atazanavir and cardiovascular risk among human immunodeficiency virus-infected patients: A systematic review
INTRODUCTION: Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular disease (CVD). While viral suppression with antiretroviral therapy decreases CVD risk overall, several studies have suggested...
Adverse drug reactions due to drug-drug interactions with proton pump inhibitors: Assessment of systematic reviews with AMSTAR method
INTRODUCTION: Many systematic reviews resulted in claims on drug-drug interactions (DDIs) with proton pump inhibitors (PPIs). Such a large number begs for consensus on the clinical significance of findings. AREAS...
The association between HIV, antiretroviral therapy and gestational diabetes mellitus: A systematic review and meta-analysis
OBJECTIVES: The widespread, chronic use of antiretroviral therapy (ART) raises questions concerning the metabolic consequences of HIV infection and treatment. Antiretroviral therapy, and specifically protease inhibitors (PIs), has been associated...
Suboptimal viral suppression rates among HIV-infected children in low- and middle-income countries: A meta-analysis
BACKGROUND: The 90-90-90 goals aim to achieve viral suppression in 90% of all HIV-infected people on antiretroviral treatment (ART), which is especially challenging in children. Global estimates of viral suppression...
Statistical monitoring-based alarming systems in modeling the AIDS epidemic in the United States, 1985-2011
BACKGROUND: Better decisions for the control of HIV/AIDS and other infectious diseases require better information. The large amount of available public health data makes it possible to extract such information...
The association of HIV-related stigma to HIV medication adherence: A systematic review and synthesis of the literature
This paper provides a review of the quantitative literature on HIV-related stigma and medication adherence, including: (1) synthesis of the empirical evidence linking stigma to adherence, (2) examination of proposed...
The impact of alcohol use and related disorders on the HIV continuum of care: A systematic review : Alcohol and the HIV continuum of care
Alcohol use is highly prevalent globally with numerous negative consequences to human health, including HIV progression, in people living with HIV (PLH). The HIV continuum of care, or treatment cascade,...
Impact of maternal HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health
Adaptation of the maternal immune system to establish maternal/fetal equilibrium is required for a successful pregnancy. Viral infections, including HIV-1 infection, can alter this maternal/fetal equilibrium, with significant consequences for...
Impact of ART on the fertility of HIV-positive women in sub-Saharan Africa
OBJECTIVE: Understanding the fertility of HIV-positive women is critical to estimating HIV epidemic trends from surveillance data and to planning resource needs and coverage of prevention of mother-to-child transmission services...
