Category Archives: Treatment
Meta-analysis of randomized controlled trials of simplified versus continued protease inhibitor-based antiretroviral therapy in HIV-1-infected patients
Objective: To evaluate the efficacy and safety of simplified maintenance therapy (SMT) compared with continued protease inhibitor (PI) therapy. Design: Meta-analysis of nine randomized controlled trials in which 833 patients...
Baseline CD4+ cell count, not viral load, correlates with virologic suppression induced by potent antiretroviral therapy
OBJECTIVE: To investigate the relationship between viral load suppression and baseline viral load as well as that between viral load suppression and baseline CD4(+) cell count. DESIGN: Meta-analysis of published...
Is the sexual behaviour of HIV patients on antiretroviral therapy safe or risky in Sub-Saharan Africa? Meta-analysis and meta-regression
Background: Reports on the sexual behavior of people on antiretroviral therapy (ART) are inconsistent. We selected 14 articles that compared the sexual behavior of people with and without ART for...
Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Sub-Saharan Africa (SSA) has the highest burden of HIV in the world and a rising prevalence of cardiometabolic disease; however, the interrelationship between HIV, antiretroviral therapy (ART) and cardiometabolic...
Costs and efficiency of integrating HIV/AIDS services with other health services: A systematic review of evidence and experience
OBJECTIVES: To review the literature on the potential efficiency gains of integrating HIV services with other health services. DESIGN: Systematic literature review. Search of electronic databases, manual searching and snowball...
Task shifting for the delivery of pediatric antiretroviral treatment: A systematic review
BACKGROUND: Pediatric antiretroviral treatment coverage in resource-limited settings continues to lag behind adults. Task shifting is an effective approach broadly used for adults, which some countries have also adopted for...
Sex differences in HIV outcomes in the highly active antiretroviral therapy era: A systematic review.
Objective: To assess sex disparities in AIDS clinical and laboratory outcomes in the HAART era. Design: Systematic review of published literature on mortality, disease progression, and laboratory outcomes among persons...
Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection
BACKGROUND: More than 34 million people are presently living with HIV infection. Antiretroviral therapy (ART) can help these people to live longer, healthier lives, but adherence to ART can be...
A systematic review of effects of concurrent strength and endurance training on the health-related quality of life and cardiopulmonary status in patients with HIV/AIDS
PURPOSE: To determine the effects of concurrent strength and endurance training (concurrent training) on the Health-Related Quality of Life (HRQOL) and cardiopulmonary status among HIV-infected patients, using a systematic search...
