Category Archives: Treatment
Endothelial dysfunction, a predictor of cardiovascular disease in HIV patients on antiretroviral therapy: A systematic review and meta-analysis
Aim Although antiretroviral therapy (ART) is available, the rate of new HIV infections is alarming. With this trend, it is anticipated that the use of ART will continue to rise,...
Virologic outcomes of antiretroviral therapy in patients with HIV-1 following bariatric surgery: A case series and review of the literature
BACKGROUND: Selection of an antiretroviral regimen for people living with HIV (PLWH) involves various clinical considerations, such as comorbidities, archived drug resistance mutations, concomitant medications, and potential drug interactions and...
Effect of intake of probiotics and probiotic fermented foods on clinical outcomes among people living with HIV: A systematic review and meta-analysis
OBJECTIVE: The objective of the study was to determine the effect of probiotics and of probiotic-fermented foods on CD4 T-cell count, viral load, anaemia and body mass index (BMI) among...
Counseling supporting HIV self-testing and linkage to care among men who have se with men: Systematic review and meta-analysis
BACKGROUND: Counseling supporting HIV self-testing (HIVST) is helpful in facilitating linkage to care and promoting behavior changes among men who have sex with men (MSM). Different levels of counseling support...
The cost-effectiveness of Dolutegravir in combination with Tenofovir and Lamivudine for HIV therapy: A systematic review
The World Health Organization (WHO) recommends dolutegravir (DTG), a human immunodeficiency virus (HIV) medicine, as the first- and second-line treatment for all populations because, when compared to an efavirenz (EFV)...
Weight loss and mortality in people living with HIV: A systematic review and meta-analysis
Background In the first reported cases of human immunodeficiency virus (HIV) infection, people living with HIV (PLHIV) suffered weight loss, which was an independent predictor of mortality. Highly active antiretroviral...
Regional variation in NAFLD prevalence and risk factors among people living with HIV in Europe: A meta-analysis
BACKGROUND AND AIM: Europe faces an elevated risk of nonalcoholic fatty liver disease (NAFLD) among people living with HIV (PLWH), contributing to the region’s highest global burden of NAFLD. However,...
Adherence to option B+ antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: A systematic review and meta-analysis
Background To assess the adherence to option B + antiretroviral therapy (ART) and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa (SSA). Methods We conducted a comprehensive search from 01st January...
Cardio-metabolic health of offspring exposed in utero to human immuno-deficiency virus and anti-retroviral treatment: A systematic review
BACKGROUND: Antiretroviral treatment (ART) use during pregnancy continues to rise as it is known to decrease the likelihood of HIV transmission from mother to child. However, it is still unknown...
Incidence and predictors of loss to follow-up among Ethiopian children on antiretroviral therapy: A systematic review and meta-analysis
Introduction Loss of follow-up (LTFU) from ART regular follow-up is one of the key acknowledged causes for the development of ART-resistant virus strains currently. It becomes a major weakness for...
HIV prevention and treatment interventions for Black men who have sex with men in Canada: Scoping systematic review
BACKGROUND: Black men who have sex with men (MSM) experience disproportionately high HIV incidence globally. A comprehensive, intersectional approach (race, gender, and sexuality or sexual behavior) in understanding the experiences...
