Category Archives: Treatment
Diagnostic accuracy of the WHO clinical staging system for detection of immunologically defined advanced HIV disease: A systematic review and meta-analysis
Introduction People with advanced HIV disease (AHD) face high risks of severe illness and death. CD4 testing enables timely diagnosis and appropriate care, yet access remains limited in many settings....
Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response
Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...
Prevalence of current substance and hazardous alcohol use among people with HIV and tuberculosis disease and its impact on tuberculosis treatment outcomes: A systematic review
Objective: To examine the prevalence of current substance and hazardous alcohol use in people with HIV and tuberculosis (TB) disease and its impact on TB treatment outcomes. Methods: A systematic review following...
Effectiveness of differentiated antiretroviral therapy delivery models for stable persons living with HIV in Africa: A systematic review and meta-analysis
Introduction: Fundamental progress has been made in HIV care, and one of the major advances was the implementation of Differentiated Service Delivery (DSD) models. DSD models are important in reducing cost...
Effectiveness of telehealth in HIV management for people living with HIV and key populations: A systematic review of models, adherence, viral suppression, and behavioral outcomes
Human Immunodeficiency Virus (HIV) is a global health problem that causes many deaths, especially in low- and middle-income countries (LMICs). Most HIV cases occur in sub-Saharan Africa and Asia. In...
Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis
Background: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). Methods: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in September 2023....
Preferences for long-acting antiretroviral therapy among people with HIV: A systematic review of discrete choice experiments
BACKGROUND: Long-acting antiretroviral therapy (LA-ART) is emerging as a promising strategy to enhance treatment satisfaction and improve the quality of life for people living with HIV (PLWH). A comprehensive understanding...
Pregnancy and neonatal outcomes of HIV infection in pregnant women in Iran: A systematic review and meta-analysis
Background HIV infection is a major public health concern among pregnant women globally. Beyond the risk of mother-to-child transmission, it can lead to serious complications and negative pregnancy and neonatal...
Body image and its associated factors among people living with HIV: A scoping review and implications for integrated care
People living with HIV (PLWH) face unique biopsychosocial challenges due to both infection and antiretroviral therapy (ART), one of which is body image disruption. This study comprehensively reviewed relevant studies...
A scoping review of mobile health for ART adherence in pregnant and breastfeeding women with HIV in sub-Saharan Africa: Preferences, acceptability, and privacy concerns
Background Interventions involving Mobile Health (mHealth) have shown promise to improve retention in care and adherence to antiretroviral therapy (ART) among pregnant or breastfeeding women living with HIV (PBWLH). However,...
Attrition rate of antiretroviral therapy and its influencing factors among Chinese people living with HIV/AIDS: A meta-analysis and system review
Objective To systematically evaluate the attrition rate of PWH undergoing ART and its influencing factors. Methods We systematically searched Embase, PubMed, Web of Science, The Cochrane Library, VIP, WanFang, CNKI,...
