Category Archives: Treatment
Contemporary issues on the epidemiology and antiretroviral adherence of HIV-infected adolescents in sub-Saharan Africa: A narrative review
INTRODUCTION: Adolescents are a unique and sometimes neglected group in the planning of healthcare services. This is the case in many parts of sub-Saharan Africa, where more than eight out...
The HIV care cascade: A systematic review of data sources, methodology and comparability
INTRODUCTION: The cascade of HIV diagnosis, care and treatment (HIV care cascade) is increasingly used to direct and evaluate interventions to increase population antiretroviral therapy (ART) coverage, a key component...
Is there scope for cost savings and efficiency gains in HIV services? A systematic review of the evidence from low- and middle-income countries
OBJECTIVE: To synthesize the data available–on costs, efficiency and economies of scale and scope–for the six basic programmes of the UNAIDS Strategic Investment Framework, to inform those planning the scale-up...
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: A systematic review and meta-analysis
OBJECTIVES: Antiretroviral therapy (ART) reduces the morbidity and mortality of patients infected with HIV. Standard ART includes either nevirapine or efavirenz, however the efficacy of these drugs is limited in...
Incidence of HIV-associated tuberculosis among individuals taking combination antiretroviral therapy: A systematic review and meta-analysis.
BACKGROUND: Knowledge of tuberculosis incidence and associated factors is required for the development and evaluation of strategies to reduce the burden of HIV-associated tuberculosis. METHODS: Systematic literature review and meta-analysis...
Adherence to HIV postexposure prophylaxis: A systematic review and meta-analysis
INTRODUCTION: We evaluated variations in completion rates for HIV postexposure prophylaxis (PEP) according to the exposure type (occupational, nonoccupational, and sexual assault), patient, and programme characteristics. METHODS: Four major databases...
Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: A systematic review and meta-analysis of randomized controlled trials
Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials comparing efavirenz and...
Interventions that retain African Americans in HIV/AIDS treatment: Implications for social work practice and research
Social workers play an important role in recognizing and addressing barriers to retention in HIV care. Although there is a large body of literature and research supporting interventions that promote...
mHealth: An updated systematic review with a focus on HIV/AIDS and tuberculosis long term management using mobile phones
OBJECTIVE: To evaluate the utilization of mobile phone technology for treatment adherence, prevention, education, data collection, monitoring long-term management of HIV/AIDS and TB patients. METHODS: Articles published in English language...
Evidence of increased blood pressure and hypertension risk among people living with HIV on antiretroviral therapy: A systematic review with meta-analysis
Owing to antiretroviral drug-induced endothelial dysfunction, HIV-infected patients on antiretroviral therapy (ART) may have elevated blood pressure. We conducted a systematic review and meta-analysis to estimate the effects of ART...
