Category Archives: Treatment

Pediatric palliative care for youth with HIV/AIDS: Systematic review of the literature

2013

Improvement in treatment has led to decreased death in youth with human immunodeficiency virus (HIV) in developed countries. Despite this, youth with HIV are still at risk for increased mortality...

Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort

2011

OBJECTIVES: : The relative success of liver transplantation in those with HIV compared to HIV-uninfected individuals remains a point of intense debate. We aimed to evaluate the effectiveness of liver...

Cost-effectiveness of adherence interventions for highly active antiretroviral therapy: A systematic review

2013

Objectives: The objective of this systematic review was to evaluate the cost-effectiveness of interventions aiming to increase the adherence to highly active antiretroviral therapy (HAART) in HIV-infected patients in developed...

Selenium supplementation in HIV-infected patients: Is there any potential clinical benefit?

2009

In HIV-infected patients undergoing antiretroviral therapy, the question of whether selenium supplementation has any therapeutic benefit is still open. With recent popular coverage of this issue, many patients have considered...

Psychological treatment of depressive symptoms in patients with medical disorders: A meta-analysis

2010

OBJECTIVE: It is widely acknowledged that the prevalence of depression in the general population is high, but that it is even higher for patients with medical disorders. Yet, the effectiveness...

Does highly active antiretroviral therapy improve neurocognitive function? A systematic review

2010

Highly active antiretroviral therapy (HAART) reduces the incidence of human immunodeficiency virus (HIV) dementia (HAD), whereas the overall prevalence appears to have increased. Recent changes to diagnostic nosology have emphasized...

Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials

2008

OBJECTIVES: We performed a meta-analysis to assess the efficacy and safety of switching from protease inhibitor (PI)- to nevirapine (NVP)-based regimens in HIV-infected patients in whom virological suppression had been...

Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS

2013

Background: UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse...

Obstacles and proposed solutions to effective antiretroviral therapy in resource-limited settings

2009

More than 3 million people were receiving antiretroviral therapy (ART) at the end of 2007, but this number represents only 31% of people clinically eligible for ART in resource-limited settings....

Safety of efavirenz in first-trimester of pregnancy: A systematic review and meta-analysis of outcomes from observational cohorts

2010

Introduction: Data on efavirenz safety in first trimester pregnancy are conflicting. We conducted a systematic review and meta-analysis of the available evidence from observational cohorts., Methods: We ran duplicate searches...

Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults

2006

BACKGROUND: A favourable regimen for people infected with HIV/AIDS is one that provides optimal efficacy, durability of antiretroviral activity, tolerability, and has low adverse effects and drug-drug interactions. The combination...

Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: Systematic review and meta-analysis of randomized controlled trials

2010

OBJECTIVES: To compare lipid profiles in HIV-infected adults receiving atazanavir-based regimens. METHODS: We conducted a systematic review of randomized controlled trials (RCTs) comparing atazanavir or atazanavir/ritonavir with a comparator and...

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